https://en.formulasearchengine.com/w/api.php?action=feedcontributions&feedformat=atom&user=141.14.245.16formulasearchengine - User contributions [en]2026-08-12T12:56:22ZUser contributionsMediaWiki 1.47.0-wmf.7https://en.formulasearchengine.com/w/index.php?title=Glucose-1-phosphate_adenylyltransferase&diff=21205Glucose-1-phosphate adenylyltransferase2010-10-29T10:43:26Z<p>141.14.245.16: </p>
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<div>{{enzyme<br />
| Name = glycerate kinase<br />
| EC_number = 2.7.1.31<br />
| CAS_number = 9026-61-3<br />
| IUBMB_EC_number = 2/7/1/31<br />
| GO_code = 0008887<br />
| image = <br />
| width = <br />
| caption = <br />
}}<br />
{{Pfam box |Symbol = Glyc_kinase |Name = Glycerate kinase |Pfam = PF02595 |InterPro = IPR004381 |PROSITE = |PDB = {{PDB|1to6}} }}<br />
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In [[enzymology]], a '''glycerate kinase''' ({{EC number|2.7.1.31}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]<br />
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:ATP + (R)-glycerate <math>\rightleftharpoons</math> ADP + 3-phospho-(R)-glycerate<br />
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Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]] and [[(R)-glycerate]], whereas its two [[product (chemistry)|products]] are [[adenosine diphosphate|ADP]] and [[3-phospho-(R)-glycerate]].<br />
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This enzyme belongs to the family of [[transferase]]s, specifically those transferring phosphorus-containing groups ([[phosphotransferase]]s) with an alcohol group as acceptor. The systematic name of this enzyme class is '''ATP:(R)-glycerate 3-phosphotransferase'''. Other names in common use include '''glycerate kinase (phosphorylating)''', '''D-glycerate 3-kinase''', '''D-glycerate kinase''', '''glycerate-3-kinase''', '''GK''', '''D-glyceric acid kinase''', and '''ATP:D-glycerate 2-phosphotransferase'''. This enzyme participates in 3 [[metabolism|metabolic pathways]]: [[serine]]/[[glycine]]/[[threonine]] metabolism, [[glycerolipid]] metabolism, and [[glyoxylate]]-[[dicarboxylate]] metabolism. <br />
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==Structural studies==<br />
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As of late 2007, 3 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1TO6}}, {{PDB link|1X3L}}, and {{PDB link|2B8N}}.<br />
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==References==<br />
{{reflist|1}}<br />
* {{cite journal | author = Doughty CC, Hayashi JA, Guenther HL | date = 1966 | title = Purification and properties of D-glycerate 3-kinase from Escherichia coli | journal = J. Biol. Chem. | volume = 241 | pages = 568&ndash;72 | pmid = 5325263 | issue = 3 }}<br />
* {{cite journal | author = ICHIHARA A, GREENBERG DM | date = 1957 | title = Studies on the purification and properties of D-glyceric acid kinase of liver | journal = J. Biol. Chem. | volume = 225 | pages = 949&ndash;58 | pmid = 13416296 | issue = 2 }}<br />
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{{enzyme-stub}}<br />
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[[Category:EC 2.7.1]]<br />
[[Category:Enzymes of known structure]]</div>141.14.245.16