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{{DISPLAYTITLE:''Z''-test}}
{{chembox
A '''''Z''-test''' is any [[statistics|statistical]] [[statistical hypothesis testing|test]] for which the [[probability distribution|distribution]] of the [[test statistic]] under the [[null hypothesis]] can be approximated by a [[normal distribution]]. Because of the [[central limit theorem]], many test statistics are approximately normally distributed for large samples. For each significance level, the ''Z''-test has a single critical value (for example, 1.96 for 5% two tailed) which makes it more convenient than the [[Student's t-test|Student's ''t''-test]] which has separate critical values for each sample size. Therefore, many statistical tests can be conveniently performed as approximate ''Z''-tests if the sample size is large or the population variance known. If the population variance is unknown (and therefore has to be estimated from the sample itself) and the sample size is not large (n < 30), the Student's ''t''-test may be more appropriate.
| verifiedrevid = 444009999
|  Name = '''Mesitylene'''
|  ImageFileL1_Ref = {{chemboximage|correct|??}}
| ImageFileL1 = Mesitylene-2D-skeletal.png
|   ImageSizeL1 = 120px
|   ImageNameL1 = Mesitylene
|   ImageFileR1 = Mesitylene-3D-vdW.png
|  ImageSizeR1 = 120px
|  ImageNameR1 = Mesitylene
|  IUPACName = 1,3,5-Trimethylbenzene
|  OtherNames = Mesitylene<br />''sym''-Trimethylbenzene
| Section1 = {{Chembox Identifiers
|  ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 7659
| PubChem = 7947
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = C14508
| InChI = 1/C9H12/c1-7-4-8(2)6-9(3)5-7/h4-6H,1-3H3
| InChIKey = AUHZEENZYGFFBQ-UHFFFAOYAK
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C9H12/c1-7-4-8(2)6-9(3)5-7/h4-6H,1-3H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = AUHZEENZYGFFBQ-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 108-67-8
|  EINECS = 203-604-4
|  ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 34833
| SMILES = Cc1cc(cc(c1)C)C
}}
| Section2 = {{Chembox Properties
|  Formula = C<sub>9</sub>H<sub>12</sub>
|  MolarMass = 120.19 g/mol
|  Density = 0.8637 g/cm³ at 20 °C
|  MeltingPt = −44.8 °C
|  BoilingPt = 164.7 °C
  }}
| Section3 = {{Chembox Structure
|  Dipole = 0.047 [[Debye|D]] <ref>{{Cite journal | doi = 10.1016/j.atmosenv.2004.01.019| title = Proton transfer reaction rate constants between hydronium ion
(H<sub>3</sub>O<sup>+</sup>) and volatile organic compounds | year = 2004 | last1 = Zhao| first1 = Jun | last2 = Zhang | first2 = Renyi | journal = Atmospheric Environment | volume = 38 | issue = 14 | pages =  2177–2185 }}</ref>
}}
| Section7 = {{Chembox Hazards
|  Autoignition =
|  EUClass =
|  EUIndex =
|  ExploLimits =
|  ExternalMSDS = [http://www.sigmaaldrich.com/MSDS/MSDS/DisplayMSDSPage.do?country=US&language=en&productNumber=63908&brand=FLUKA&PageToGoToURL=http%3A%2F%2Fwww.sigmaaldrich.com%2Fcatalog%2Fsearch%3Finterface%3DAll%26term%3Dmesitylene%26lang%3Den%26region%3DUS%26focus%3Dproduct%26N%3D0%2B220003048%2B219853269%2B219853286%26mode%3Dmatch%2520partialmax Safety data from Sigma Aldrich]
|  FlashPt = 50 °C<ref>[http://www.cdc.gov/niosh/npg/npgd0639.html CDC - NIOSH Pocket Guide to Chemical Hazards]</ref>
|  LD50 =
|  MainHazards =
|  NFPA-H =
|  NFPA-F =
|  NFPA-R =
|  NFPA-O =
|  PEL =
|  RPhrases =
|  RSPhrases =
|  SPhrases = }}
}}


If ''T'' is a statistic that is approximately normally distributed under the null hypothesis, the next step in performing a ''Z''-test is to estimate the [[expected value]] θ of ''T'' under the null hypothesis, and then obtain an estimate ''s'' of the [[standard deviation]] of ''T''. After that the [[standard score]] ''Z''&nbsp;=&nbsp;(''T''&nbsp;&minus;&nbsp;θ)&nbsp;/&nbsp;''s'' is calculated, from which [[one- and two-tailed tests|one-tailed and two-tailed]] [[p-values|''p''-values]] can be calculated as Φ(&minus;''Z'') (for upper-tailed tests), Φ(''Z'') (for lower-tailed tests) and 2Φ(&minus;|''Z''|) (for two-tailed tests) where Φ is the standard [[normal distribution|normal]] [[cumulative distribution function]].
'''Mesitylene''' or '''1,3,5-trimethylbenzene''' is a derivative of [[benzene]] with three [[methyl]] [[substituent]]s symmetrically placed on the ring. Isomeric trimethylbenzenes include [[1,2,4-Trimethylbenzene|1,2,4-trimethylbenzene]] (pseudocumene) and [[1,2,3-Trimethylbenzene|1,2,3-trimethylbenzene]] (hemimellitene).  All three compounds have the [[Chemical formula|formula]] C<sub>6</sub>H<sub>3</sub>(CH<sub>3</sub>)<sub>3</sub>, which is commonly abbreviated C<sub>6</sub>H<sub>3</sub>Me<sub>3</sub>.  Mesitylene is a colourless liquid with sweet aromatic odor.  It is a component of [[coal tar]], which is its traditional source.  It is a precursor to diverse [[fine chemicals]].  The '''mesityl''' group (Mes) is a  substituent with the formula C<sub>6</sub>H<sub>2</sub>Me<sub>3</sub> and is found in various other compounds.<ref name=Ullmanns/>


==Use in location testing==
== Preparation ==
Mesitylene is prepared by equilibration of [[xylene]] (or simple methyl [[alkylation]] of it) over solid [[acid catalyst]]:<ref name=Ullmanns>Karl Griesbaum, Arno Behr, Dieter Biedenkapp, Heinz-Werner Voges, Dorothea Garbe, Christian Paetz, Gerd Collin, Dieter Mayer, Hartmut Höke “Hydrocarbons” in Ullmann's Encyclopedia of Industrial Chemistry 2002 Wiley-VCH, Weinheim. {{DOI|10.1002/14356007.a13_227}}.</ref>
:2 C<sub>6</sub>H<sub>4</sub>(CH<sub>3</sub>)<sub>2</sub>  ⇌ C<sub>6</sub>H<sub>3</sub>(CH<sub>3</sub>)<sub>3</sub>  +  C<sub>6</sub>H<sub>5</sub>CH<sub>3</sub>
:C<sub>6</sub>H<sub>4</sub>(CH<sub>3</sub>)<sub>2</sub>  +  CH<sub>3</sub>OH  →  C<sub>6</sub>H<sub>3</sub>(CH<sub>3</sub>)<sub>3</sub>  +  H<sub>2</sub>O


The term "''Z''-test" is often used to refer specifically to the [[location test|one-sample location test]] comparing the mean of a set of measurements to a given constant. If the observed data ''X''<sub>1</sub>, ..., ''X''<sub>n</sub> are (i) uncorrelated, (ii) have a common mean μ, and (iii) have a common variance σ<sup>2</sup>, then the sample average <span style="text-decoration: overline">''X''</span> has mean μ and variance σ<sup>2</sup>&nbsp;/&nbsp;''n''. If our null hypothesis is that the mean value of the population is a given number μ<sub>0</sub>, we can use <span style="text-decoration: overline">''X''</span>&nbsp;&minus;μ<sub>0</sub> as a test-statistic, rejecting the null hypothesis if <span style="text-decoration: overline">''X''</span>&nbsp;&minus;μ<sub>0</sub> is large.
In the laboratory, it can be prepared by trimerization of [[propyne]], also requiring an [[acid catalyst]], affords a mixture of 1,3,5- and 1,2,4-trimethylbenzenes.


To calculate the standardized statistic ''Z''&nbsp;=&nbsp;(<span style="text-decoration: overline">''X''</span> &nbsp;&minus;&nbsp; μ<sub>0</sub>)&nbsp;/&nbsp;''s'', we need to either know or have an approximate value for σ<sup>2</sup>, from which we can calculate ''s''<sup>2</sup>&nbsp;=&nbsp;σ<sup>2</sup>&nbsp;/&nbsp;''n''. In some applications, σ<sup>2</sup> is known, but this is uncommon. If the sample size is moderate or large, we can substitute the [[Sample_variance#Population_variance_and_sample_variance|sample variance]] for σ<sup>2</sup>, giving a ''plug-in'' test. The resulting test will not be an exact ''Z''-test since the uncertainty in the sample variance is not accounted for &mdash; however, it will be a good approximation unless the sample size is small. A [[t-test|''t''-test]] can be used to account for the uncertainty in the sample variance when the sample size is small and the data are exactly [[normal distribution|normal]]. There is no universal constant at which the sample size is generally considered large enough to justify use of the plug-in test. Typical rules of thumb range from 20 to 50 samples. For larger sample sizes, the ''t''-test procedure gives almost identical ''p''-values as the ''Z''-test procedure.
Catalyzing and [[Dehydration|dehydrating]] by [[sulfuric acid]], [[trimerization]] of [[acetone]] via [[aldol condensation]] also affords mesitylene.


Other location tests that can be performed as ''Z''-tests are the two-sample location test and the [[paired difference test]].
== Reactions ==
Oxidation of mesitylene with [[nitric acid]] affords [[trimesic acid]] ( C<sub>6</sub>H<sub>3</sub>(CO<sub>2</sub>H)<sub>3</sub>).  Using the milder oxidant [[manganese dioxide]], one obtains 3,5- dimethylbenzaldehyde.  With metal centers it functions as a ligand, one example being ([[hapticity|η<sup>6</sup>]]-C<sub>6</sub>H<sub>3</sub>Me<sub>3</sub>)Mo(CO)<sub>3</sub>.<ref>Girolami, G. S.; Rauchfuss, T. B. and Angelici, R. J., Synthesis and Technique in Inorganic Chemistry, University Science Books: Mill Valley, CA, 1999. ISBN 0-93570248-2.</ref>


== Conditions ==
== Applications ==
It is commonly used as a [[solvent]] in the laboratory.  It serves as a ligand in organometallic chemistry, one example being ([[hapticity|η<sup>6</sup>]]-C<sub>6</sub>H<sub>3</sub>Me<sub>3</sub>)Mo(CO)<sub>3</sub>.


For the ''Z''-test to be applicable, certain conditions must be met.
In the electronics industry, mesitylene has also been used as a [[photographic developer|developer]] for photopatternable [[silicone]]s due to its solvent properties.


* [[Nuisance parameter]]s should be known, or estimated with high accuracy (an example of a nuisance parameter would be the [[standard deviation]] in a one-sample location test). ''Z''-tests focus on a single parameter, and treat all other unknown parameters as being fixed at their true values. In practice, due to [[Slutsky's theorem]], "plugging in" [[consistent estimator|consistent]] estimates of nuisance parameters can be justified. However if the sample size is not large enough for these estimates to be reasonably accurate, the ''Z''-test may not perform well.
1,3,5-Trimethylbenzene is also a major urban [[volatile organic compound]] (VOC) which results from [[combustion]]. It plays a significant role in aerosol and [[tropospheric ozone]] formation as well as other reactions in [[atmospheric chemistry]].


* The test statistic should follow a [[normal distribution]]. Generally, one appeals to the [[central limit theorem]] to justify assuming that a test statistic varies normally. There is a great deal of statistical research on the question of when a test statistic varies approximately normally. If the variation of the test statistic is strongly non-normal, a ''Z''-test should not be used.
The three [[aromatic]] hydrogen atoms of mesitylene are in identical chemical shift environments. Therefore, they only give a single peak near 6.8 ppm in the [[1H NMR]] spectrum. For this reason, mesitylene is sometimes used as an [[internal standard]] in NMR samples that contain aromatic protons.<ref>http://chemicalland21.com/industrialchem/organic/MESITYLENE.htm</ref>


If estimates of nuisance parameters are plugged in as discussed above, it is important to use estimates appropriate for the way the data were [[sampling (statistics)|sampled]]. In the special case of ''Z''-tests for the one or two sample location problem, the usual sample [[standard deviation]] is only appropriate if the data were collected as an independent sample.
== History ==
Mesitylene was first prepared in 1837 by [[Robert Kane (chemist)|Robert Kane]], an Irish chemist, by heating acetone with concentrated sulfuric acid.<ref>Robert  Kane (1839) [http://books.google.com/books?id=AuIcAQAAMAAJ&pg=PA99#v=onepage&q&f=false "On a series of combinations derived from pyroacetic spirit] [acetone]" ''Transactions of the Royal Irish Academy'', vol. 18, pages 99–125.</ref>  He named his new substance "mesitylene" because the German chemist [[Carl Reichenbach]] had named acetone "mesit" (from the Greek μεσίτης, the mediator),<ref>Reichenbach's research is excerpted in:  C. Reichenbach (1834) [http://books.google.com/books?id=P0s9AAAAcAAJ&pg=PA298#v=onepage&q&f=false "Ueber Mesit (Essiggeist) und Holzgeist"] (On mesit (spirit of vinegar) and wood spirits), ''Annalen der Pharmacie'', vol. 10, no. 3, pages 298–314.</ref> and Kane believed that his reaction had dehydrated mesit, converting it to an [[alkene]], "mesitylene".<ref>For an explanation of the original of the name "mesitylene", see also:  Henry E. Roscoe, ''A Treatise on Chemistry'' (New York, New York: D. Appleton and Co., 1889), vol. III, [http://books.google.com/books?id=atXNAAAAMAAJ&pg=PA102#v=onepage&q&f=false page 102], footnote 2.</ref>  However, Kane's determination of the chemical composition ("empirical formula") of mesitylene was incorrect.  The correct empirical formula was provided by [[August Wilhelm von Hofmann|August W. von Hofmann]] in 1849.<ref>A.W. Hofmann (1849) "On the composition of mesitilole [mesitylene], and some of its derivatives", ''The Quarterly Journal of the Chemical Society of London'', vol. 2, [http://books.google.com/books?id=oKAwAAAAYAAJ&pg=PA104#v=onepage&q&f=false pages 104–115].  (Note:  The empirical formula of mesitylene as stated in Hofmann's paper ( C<sub>18</sub>H<sub>12</sub> ) is incorrect; however, this happened because Hofmann used 6 as the atomic weight of carbon, instead of the correct atomic weight of 12.  Once the correct atomic weight is used in Hofmann's calculations, his results give the correct empirical formula of C<sub>9</sub>H<sub>12</sub>.)</ref>  In 1866 [[Adolf von Baeyer]] showed that mesitylene's structure was consistent with that of 1,3,5-trimethylbenzene;<ref>Adolf von Baeyer (1866) [http://books.google.com/books?id=yYlKAAAAYAAJ&pg=RA1-PA297#v=onepage&q&f=false "Ueber die Condensationsproducte des Acetons"] (On condensation products of acetone), ''Annalen der Chemie und Pharmacie'', vol. 140, pages 297–306.</ref> however, conclusive proof that mesitylene was identical to 1,3,5-trimethylbenzene was provided by [[Albert Ladenburg]] in 1874.<ref>Albert Ladenburg (1874) "Ueber das Mesitylen" (On mesitylene), ''Berichte der deutschen chemischen Gesellschaft'', vol. 7, pages 1133–1137. {{DOI| 10.1002/cber.18740070261}}</ref>


In some situations, it is possible to devise a test that properly accounts for the variation in plug-in estimates of nuisance parameters. In the case of one and two sample location problems, a [[t-test|''t''-test]] does this.
== References ==
<references/>


== Example ==
[[Category:Hydrocarbon solvents]]
 
[[Category:Alkylbenzenes]]
Suppose that in a particular geographic region, the mean and standard deviation of scores on a reading test are 100 points, and 12 points, respectively. Our interest is in the scores of 55 students in a particular school who received a mean score of 96. We can ask whether this mean score is significantly lower than the regional mean &mdash; that is, are the students in this school comparable to a simple random sample of 55 students from the region as a whole, or are their scores surprisingly low?
 
We begin by calculating the [[standard error (statistics)|standard error]] of the mean:
 
:<math>\mathrm{SE} = \frac{\sigma}{\sqrt n} = \frac{12}{\sqrt{55}} = \frac{12}{7.42} = 1.62 \,\!</math>
 
where <math>{\sigma}</math> is the population standard deviation
 
Next we calculate the [[standard score|''z''-score]], which is the distance from the sample mean to the population mean in units of the standard error:
 
:<math>z = \frac{M - \mu}{\mathrm{SE}} = \frac{96 - 100}{1.62} = -2.47 \,\!</math>
 
In this example, we treat the population mean and variance as known, which would be appropriate if all students in the region were tested. When population parameters are unknown, a t test should be conducted instead.
 
The classroom mean score is 96, which is −2.47 standard error units from the population mean of 100. Looking up the ''z''-score in a table of the standard [[normal distribution]], we find that the probability of observing a standard normal value below -2.47 is approximately 0.5 - 0.4932 = 0.0068. This is the [[one-tailed|one-sided]] [[p-value|''p''-value]] for the null hypothesis that the 55 students are comparable to a simple random sample from the population of all test-takers. The two-sided ''p''-value is approximately 0.014 (twice the one-sided ''p''-value).
 
Another way of stating things is that with probability 1&nbsp;&minus;&nbsp;0.014&nbsp;=&nbsp;0.986, a simple random sample of 55 students would have a mean test score within 4 units of the population mean. We could also say that with 98.6% confidence we reject the [[null hypothesis]] that the 55 test takers are comparable to a simple random sample from the population of test-takers.
 
The ''Z''-test tells us that the 55 students of interest have an unusually low mean test score compared to most simple random samples of similar size from the population of test-takers. A deficiency of this analysis is that it does not consider whether the [[effect size]] of 4 points is meaningful. If instead of a classroom, we considered a subregion containing 900 students whose mean score was 99, nearly the same ''z''-score and ''p''-value would be observed. This shows that if the sample size is large enough, very small differences from the null value can be highly statistically significant. See [[statistical hypothesis testing]] for further discussion of this issue.
 
== ''Z''-tests other than location tests ==
 
Location tests are the most familiar ''Z''-tests. Another class of ''Z''-tests arises in [[maximum likelihood]] estimation of the [[parameter]]s in a [[parametric statistics|parametric]] [[statistical model]]. Maximum likelihood estimates are approximately normal under certain conditions, and their asymptotic variance can be calculated in terms of the [[Fisher information]]. The maximum likelihood estimate divided by its standard error can be used as a test statistic for the null hypothesis that the population value of the parameter equals zero. More generally, if <math>\hat{\theta}</math> is the maximum likelihood estimate of a parameter θ, and θ<sub>0</sub> is the value of θ under the null hypothesis,
 
:<math>
(\hat{\theta}-\theta_0)/{\rm SE}(\hat{\theta})
</math>
 
can be used as a ''Z''-test statistic.
 
When using a ''Z''-test for maximum likelihood estimates, it is important to be aware that the normal approximation may be poor if the sample size is not sufficiently large. Although there is no simple, universal rule stating how large the sample size must be to use a ''Z''-test, [[Monte Carlo method|simulation]] can give a good idea as to whether a ''Z''-test is appropriate in a given situation.
 
''Z''-tests are employed whenever it can be argued that a test statistic follows a normal distribution under the null hypothesis of interest. Many [[non-parametric statistics|non-parametric]] test statistics, such as [[U statistic]]s, are approximately normal for large enough sample sizes, and hence are often performed as ''Z''-tests.
 
== See also ==
* [[Normal distribution]]
* NormDis, normal probability distribution calculator
* [[Standard normal table]]
* [[Standard score]]
* [[Student's t-test|Student's ''t''-test]]
 
==References==
{{No footnotes|date=November 2009}}
* Sprinthall, R.C. (2011) Basic Statistical Analysis. 9th Edition. Pearson Education Group: 672 pp.
 
{{Statistics}}
 
[[Category:Statistical tests]]
[[Category:Normal distribution]]

Revision as of 11:44, 11 August 2014

Template:Chembox

Mesitylene or 1,3,5-trimethylbenzene is a derivative of benzene with three methyl substituents symmetrically placed on the ring. Isomeric trimethylbenzenes include 1,2,4-trimethylbenzene (pseudocumene) and 1,2,3-trimethylbenzene (hemimellitene). All three compounds have the formula C6H3(CH3)3, which is commonly abbreviated C6H3Me3. Mesitylene is a colourless liquid with sweet aromatic odor. It is a component of coal tar, which is its traditional source. It is a precursor to diverse fine chemicals. The mesityl group (Mes) is a substituent with the formula C6H2Me3 and is found in various other compounds.[1]

Preparation

Mesitylene is prepared by equilibration of xylene (or simple methyl alkylation of it) over solid acid catalyst:[1]

2 C6H4(CH3)2 ⇌ C6H3(CH3)3 + C6H5CH3
C6H4(CH3)2 + CH3OH → C6H3(CH3)3 + H2O

In the laboratory, it can be prepared by trimerization of propyne, also requiring an acid catalyst, affords a mixture of 1,3,5- and 1,2,4-trimethylbenzenes.

Catalyzing and dehydrating by sulfuric acid, trimerization of acetone via aldol condensation also affords mesitylene.

Reactions

Oxidation of mesitylene with nitric acid affords trimesic acid ( C6H3(CO2H)3). Using the milder oxidant manganese dioxide, one obtains 3,5- dimethylbenzaldehyde. With metal centers it functions as a ligand, one example being (η6-C6H3Me3)Mo(CO)3.[2]

Applications

It is commonly used as a solvent in the laboratory. It serves as a ligand in organometallic chemistry, one example being (η6-C6H3Me3)Mo(CO)3.

In the electronics industry, mesitylene has also been used as a developer for photopatternable silicones due to its solvent properties.

1,3,5-Trimethylbenzene is also a major urban volatile organic compound (VOC) which results from combustion. It plays a significant role in aerosol and tropospheric ozone formation as well as other reactions in atmospheric chemistry.

The three aromatic hydrogen atoms of mesitylene are in identical chemical shift environments. Therefore, they only give a single peak near 6.8 ppm in the 1H NMR spectrum. For this reason, mesitylene is sometimes used as an internal standard in NMR samples that contain aromatic protons.[3]

History

Mesitylene was first prepared in 1837 by Robert Kane, an Irish chemist, by heating acetone with concentrated sulfuric acid.[4] He named his new substance "mesitylene" because the German chemist Carl Reichenbach had named acetone "mesit" (from the Greek μεσίτης, the mediator),[5] and Kane believed that his reaction had dehydrated mesit, converting it to an alkene, "mesitylene".[6] However, Kane's determination of the chemical composition ("empirical formula") of mesitylene was incorrect. The correct empirical formula was provided by August W. von Hofmann in 1849.[7] In 1866 Adolf von Baeyer showed that mesitylene's structure was consistent with that of 1,3,5-trimethylbenzene;[8] however, conclusive proof that mesitylene was identical to 1,3,5-trimethylbenzene was provided by Albert Ladenburg in 1874.[9]

References

  1. ↑ 1.0 1.1 Karl Griesbaum, Arno Behr, Dieter Biedenkapp, Heinz-Werner Voges, Dorothea Garbe, Christian Paetz, Gerd Collin, Dieter Mayer, Hartmut Höke “Hydrocarbons” in Ullmann's Encyclopedia of Industrial Chemistry 2002 Wiley-VCH, Weinheim. Electronic Instrument Positions Staff (Standard ) Cameron from Clarence Creek, usually spends time with hobbies and interests which include knotting, property developers in singapore apartment For sale and boomerangs. Has enrolled in a world contiki journey. Is extremely thrilled specifically about visiting ..
  2. ↑ Girolami, G. S.; Rauchfuss, T. B. and Angelici, R. J., Synthesis and Technique in Inorganic Chemistry, University Science Books: Mill Valley, CA, 1999. ISBN 0-93570248-2.
  3. ↑ http://chemicalland21.com/industrialchem/organic/MESITYLENE.htm
  4. ↑ Robert Kane (1839) "On a series of combinations derived from pyroacetic spirit [acetone]" Transactions of the Royal Irish Academy, vol. 18, pages 99–125.
  5. ↑ Reichenbach's research is excerpted in: C. Reichenbach (1834) "Ueber Mesit (Essiggeist) und Holzgeist" (On mesit (spirit of vinegar) and wood spirits), Annalen der Pharmacie, vol. 10, no. 3, pages 298–314.
  6. ↑ For an explanation of the original of the name "mesitylene", see also: Henry E. Roscoe, A Treatise on Chemistry (New York, New York: D. Appleton and Co., 1889), vol. III, page 102, footnote 2.
  7. ↑ A.W. Hofmann (1849) "On the composition of mesitilole [mesitylene], and some of its derivatives", The Quarterly Journal of the Chemical Society of London, vol. 2, pages 104–115. (Note: The empirical formula of mesitylene as stated in Hofmann's paper ( C18H12 ) is incorrect; however, this happened because Hofmann used 6 as the atomic weight of carbon, instead of the correct atomic weight of 12. Once the correct atomic weight is used in Hofmann's calculations, his results give the correct empirical formula of C9H12.)
  8. ↑ Adolf von Baeyer (1866) "Ueber die Condensationsproducte des Acetons" (On condensation products of acetone), Annalen der Chemie und Pharmacie, vol. 140, pages 297–306.
  9. ↑ Albert Ladenburg (1874) "Ueber das Mesitylen" (On mesitylene), Berichte der deutschen chemischen Gesellschaft, vol. 7, pages 1133–1137. Electronic Instrument Positions Staff (Standard ) Cameron from Clarence Creek, usually spends time with hobbies and interests which include knotting, property developers in singapore apartment For sale and boomerangs. Has enrolled in a world contiki journey. Is extremely thrilled specifically about visiting .
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