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{{protein
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| Name = aspartoacylase (Canavan disease)
| caption =
| image =
| width =
| HGNCid = 756
| Symbol = ASPA
| AltSymbols =
| EntrezGene = 443
| OMIM = 608034
| RefSeq = NM_000049
| UniProt = P45381
| PDB =
| ECnumber = 3.5.1.15
| Chromosome = 17
| Arm = p
| Band = 13
| LocusSupplementaryData = -ter
}}
{{protein
| Name = aspartoacylase (aminocyclase) 3
| caption =
| image =
| width =
| HGNCid = 24104
| Symbol = ACY3
| AltSymbols =
| EntrezGene = 91703
| OMIM =
| RefSeq = NM_080658
| UniProt = Q96HD9
| PDB =
| ECnumber =
| Chromosome = 11
| Arm = q
| Band = 13
| LocusSupplementaryData =
}}
'''Aspartoacylase''' ({{EC number|3.5.1.15}}, ''aminoacylase II'', ''N-acetylaspartate amidohydrolase'', ''acetyl-aspartic deaminase'', ''acylase II'') is a [[hydrolase]] [[enzyme]]  with system name ''N-acyl-L-aspartate amidohydrolase''.,<ref>{{cite journal | title = Aminoacylase. Amino acid aminoacylases I and II from hog kidney |author = Birnbaum, S.M. |journal = Methods Enzymol. |year = 1955 |volume = 2 |pages = 115–119 |pmid = }}</ref><ref>{{cite journal | title = Specificity of amino acid acylases |author = Birnbaum, S.M., Levintow, L., Kingsley, R.B. and Greenstein, J.P. |journal = J. Biol. Chem. |year = 1952 |volume = 194 |pages = 455–470 |pmid = 14927637}}</ref> which breaks down [[N-Acetylaspartate|''N''-acetylaspartate]]. A deficiency is associated with [[Canavan disease]].This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]
 
: N-acyl-L-aspartate + H<sub>2</sub>O <math>\rightleftharpoons</math> a [[carboxylate]] + L-[[aspartate]]
 
== References ==
{{reflist}}
 
==External links==
* {{MeshName|aspartoacylase}}
 
{{Carbon-nitrogen non-peptide hydrolases}}
 
[[Category:Hydrolases acting on nonpeptide C-N bonds]]
 
 
{{hydrolase-stub}}

Latest revision as of 15:41, 23 November 2014

Friends call him Royal. I've usually loved residing in Idaho. Playing crochet is a factor that I'm totally addicted to. Interviewing is what I do in my day occupation.

Stop by my web site ... extended auto warranty; please click the next web page,