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{{enzyme
| Name = dTDP-4-amino-4,6-dideoxy-D-glucose transaminase
| EC_number = 2.6.1.33
| CAS_number = 9023-19-2
| IUBMB_EC_number = 2/6/1/33
| GO_code = 0019179
| image =
| width =
| caption =  
}}
{{lowercase}}
In [[enzymology]], a '''dTDP-4-amino-4,6-dideoxy-D-glucose transaminase''' ({{EC number|2.6.1.33}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate <math>\rightleftharpoons</math> dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[dTDP-4-amino-4,6-dideoxy-D-glucose]] and [[2-oxoglutarate]], whereas its two [[product (chemistry)|products]] are [[dTDP-4-dehydro-6-deoxy-D-glucose]] and [[L-glutamate]].
 
This enzyme belongs to the family of [[transferase]]s, specifically the [[transaminases]], which transfer nitrogenous groups. The systematic name of this enzyme class is '''dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase'''. Other names in common use include '''thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase''', '''thymidine diphospho-4-amino-6-deoxyglucose aminotransferase''', '''thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase''', '''thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase''', and '''TDP-4-keto-6-deoxy-D-glucose transaminase'''. This enzyme participates in [[nucleotide sugars metabolism]]. It employs one [[cofactor (biochemistry)|cofactor]], [[pyridoxal phosphate]].
 
==References==
{{reflist|1}}
* {{cite journal | author = Matsuhashi M, Strominger JL | date = 1966 | title = Thymidine diphosphate 4-acetamido-2,6-dideoxyhexoses. 3 Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Escherichia coli strain B | journal = J. Biol. Chem. | volume = 241 | pages = 4738&ndash;44  | pmid = 5332731 | issue = 20 }}
 
{{transferase-stub}}
 
[[Category:EC 2.6.1]]
[[Category:Pyridoxal phosphate enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 22:47, 17 March 2013

Template:Enzyme Template:Lowercase In enzymology, a dTDP-4-amino-4,6-dideoxy-D-glucose transaminase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate

Thus, the two substrates of this enzyme are dTDP-4-amino-4,6-dideoxy-D-glucose and 2-oxoglutarate, whereas its two products are dTDP-4-dehydro-6-deoxy-D-glucose and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase. Other names in common use include thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase, thymidine diphospho-4-amino-6-deoxyglucose aminotransferase, thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase, thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase, and TDP-4-keto-6-deoxy-D-glucose transaminase. This enzyme participates in nucleotide sugars metabolism. It employs one cofactor, pyridoxal phosphate.

References

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