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{{Infobox enzyme
| Name = Molybdopterin synthase
| EC_number = 2.8.1.12
| CAS_number =
| IUBMB_EC_number = 2/8/1/12
| GO_code =
| image =
| width =
| caption =
}}
'''Molybdopterin synthase''' ({{EC number|2.8.1.12}}, ''MPT synthase'') is an [[enzyme]] required to synthesize [[molybdenum cofactor]] (MoCo)
from precursor Z (now known as [[cyclic pyranopterin monophosphate]]).<ref>{{cite journal | title = Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency |author = Daniels, J.N., Wuebbens, M.M., Rajagopalan, K.V. and Schindelin, H. |journal = Biochemistry |year = 2008 |volume = 47 |pages = 615–626 |pmid = 18092812}}</ref><ref>{{cite journal | title = Mechanistic and mutational studies of ''Escherichia coli'' molybdopterin synthase clarify the final step of molybdopterin biosynthesis |author = Wuebbens, M.M. and Rajagopalan, K.V. |journal = J. Biol. Chem. |year = 2003 |volume = 278 |pages = 14523–14532 |pmid = 12571226}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]
 
: cyclic pyranopterin monophosphate + 2 [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH<sub>2</sub>-C(O)SH + H<sub>2</sub>O <math>\rightleftharpoons</math> [[molybdopterin]] + 2 molybdopterin-synthase sulfur-carrier protein
 
It is [[heterodimeric]] and coded for by the [[MOCS2]] gene.<ref>{{cite journal | last1=Sloan | first1=J | last2=Kinghorn | first2=JR | last3=Unkles | first3=SE | title=The two subunits of human molybdopterin synthase: evidence for a bicistronic messenger RNA with overlapping reading frames | journal=Nucleic Acids Research | volume=27 | issue=3 | pages=854–8 | year=1999 | pmc=148257| pmid =9889283 | doi=10.1093/nar/27.3.854}}</ref>
 
==References==
{{reflist}}
 
[[Category:Enzymes]]
 
 
{{biochem-stub}}

Latest revision as of 20:51, 4 June 2013

Template:Infobox enzyme Molybdopterin synthase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika., MPT synthase) is an enzyme required to synthesize molybdenum cofactor (MoCo) from precursor Z (now known as cyclic pyranopterin monophosphate).[1][2] This enzyme catalyses the following chemical reaction

cyclic pyranopterin monophosphate + 2 [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + H2O molybdopterin + 2 molybdopterin-synthase sulfur-carrier protein

It is heterodimeric and coded for by the MOCS2 gene.[3]

References

43 year old Petroleum Engineer Harry from Deep River, usually spends time with hobbies and interests like renting movies, property developers in singapore new condominium and vehicle racing. Constantly enjoys going to destinations like Camino Real de Tierra Adentro.


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    In its statement, the singapore property listing - website link, government claimed that the majority citizens buying their first residence won't be hurt by the new measures. Some concessions can even be prolonged to chose teams of consumers, similar to married couples with a minimum of one Singaporean partner who are purchasing their second property so long as they intend to promote their first residential property. Lower the LTV limit on housing loans granted by monetary establishments regulated by MAS from 70% to 60% for property purchasers who are individuals with a number of outstanding housing loans on the time of the brand new housing purchase. Singapore Property Measures - 30 August 2010 The most popular seek for the number of bedrooms in Singapore is 4, followed by 2 and three. Lush Acres EC @ Sengkang

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    Extending the tax exemption would help. The exemption, which may be as a lot as $2 million per family, covers individuals who negotiate a principal reduction on their existing mortgage, sell their house short (i.e., for lower than the excellent loans), or take part in a foreclosure course of. An extension of theexemption would seem like a common-sense means to assist stabilize the housing market, but the political turmoil around the fiscal-cliff negotiations means widespread sense could not win out. Home Minority Chief Nancy Pelosi (D-Calif.) believes that the mortgage relief provision will be on the table during the grand-cut price talks, in response to communications director Nadeam Elshami. Buying or promoting of blue mild bulbs is unlawful.

    A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running

    The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more

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