6-carboxyhexanoate—CoA ligase: Difference between revisions

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{{enzyme
| Name = 4-amino-4-deoxychorismate synthase
| EC_number = 2.6.1.85
| CAS_number = 132264-37-0
| IUBMB_EC_number = 2/6/1/85
| GO_code = 0046820
| image =
| width =
| caption =
}}
In [[enzymology]], an '''aminodeoxychorismate synthase''' ({{EC number|2.6.1.85}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


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:chorismate + L-glutamine <math>\rightleftharpoons</math> 4-amino-4-deoxychorismate + L-glutamate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[chorismate]] and [[L-glutamine]], whereas its two [[product (chemistry)|products]] are [[4-amino-4-deoxychorismate]] and [[L-glutamate]].
 
This enzyme belongs to the family of [[ligase]]s, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with glutamine as amido-N-donor. The systematic name of this enzyme class is '''chorismate:L-glutamine amido-ligase'''. Other names in common use include '''ADC synthase''', '''4-amino-4-deoxychorismate synthase''', and '''PabB'''. This enzyme participates in [[folate biosynthesis]].
 
==References==
{{reflist|1}}
* {{cite journal | author = Ye QZ, Liu J, Walsh CT | date = 1990 | title = p-Aminobenzoate synthesis in Escherichia coli: purification and characterization of PabB as aminodeoxychorismate synthase and enzyme X as aminodeoxychorismate lyase | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 87 | pages = 9391&ndash;5  | pmid = 2251281 | doi = 10.1073/pnas.87.23.9391 | issue = 23 | pmc = 55171 }}
* {{cite journal | author = Viswanathan VK, Green JM, Nichols BP | date = 1995 | title = Kinetic characterization of 4-amino 4-deoxychorismate synthase from Escherichia coli | journal = J. Bacteriol| volume = 177 | pages = 5918&ndash;23  | pmid = 7592344 | issue = 20 | pmc = 177419 }}
 
{{ligase-stub}}
 
[[Category:EC 2.6.1]]
[[Category:Enzymes of unknown structure]]

Revision as of 01:02, 21 August 2013

Template:Enzyme In enzymology, an aminodeoxychorismate synthase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

chorismate + L-glutamine 4-amino-4-deoxychorismate + L-glutamate

Thus, the two substrates of this enzyme are chorismate and L-glutamine, whereas its two products are 4-amino-4-deoxychorismate and L-glutamate.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with glutamine as amido-N-donor. The systematic name of this enzyme class is chorismate:L-glutamine amido-ligase. Other names in common use include ADC synthase, 4-amino-4-deoxychorismate synthase, and PabB. This enzyme participates in folate biosynthesis.

References

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Template:Ligase-stub