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The '''Reid Index''' is a mathematical relationship that exists in a human [[bronchus]] section observed under the [[microscope]]. It is defined as ratio between the thickness of the submucosal [[mucus]] secreting [[gland]]s and the thickness between the [[epithelium]] and [[cartilage]] that covers the [[Bronchus|bronchi]]. The Reid index is not of diagnostic use ''in vivo'' since it requires a dissection of the airway tube, but it has value in ''post mortem'' evaluations and for research.<ref>B. Karger, T. Fracasso, B. Brinkmann and T. Bajanowski. ''Evaluation of the Reid index in infants and cases of SIDS''. International Journal of Legal Medicine. Volume 118, Number 4 / August, 2004. [http://www.springerlink.com/content/5eey33q9ul81n8h6/]</ref> | |||
==Calculation== | |||
:<math>\ RI = \frac {gland}{wall}</math> | |||
where: | |||
: '''RI''' is the Reid Index | |||
:''wall'' is the thickness of the airway wall between the [[epithelium]] and the [[cartilage]]'s [[perichondrium]] | |||
:''gland'' is the thickness of the mucous producing gland at the location of inspection. | |||
==Interpretation== | |||
A normal Reid Index should be smaller than 0.4, the thickness of the wall is always more than double the thickness of the glands it contains. A greater value is the most pathognomonic indicator of chronic bronchitis. | |||
[[Hyperplasia]] and [[hypertrophy]] of mucous glands as in [[chronic bronchitis]]<ref>[http://www.som.tulane.edu/classware/pathology/medical_pathology/New_for_98/Lung_Review/Lung-20.html School of Medicine, Tulane University]</ref> causes them to be present at deeper levels in the bronchial wall and thicker in size, thus increasing the Reid Index beyond the normal value. | |||
==References== | |||
{{reflist|2}} | |||
{{Eponymous medical signs for respiratory system}} | |||
[[Category:Respiratory system]] | |||
Revision as of 14:54, 14 December 2013
The Reid Index is a mathematical relationship that exists in a human bronchus section observed under the microscope. It is defined as ratio between the thickness of the submucosal mucus secreting glands and the thickness between the epithelium and cartilage that covers the bronchi. The Reid index is not of diagnostic use in vivo since it requires a dissection of the airway tube, but it has value in post mortem evaluations and for research.[1]
Calculation
where:
- RI is the Reid Index
- wall is the thickness of the airway wall between the epithelium and the cartilage's perichondrium
- gland is the thickness of the mucous producing gland at the location of inspection.
Interpretation
A normal Reid Index should be smaller than 0.4, the thickness of the wall is always more than double the thickness of the glands it contains. A greater value is the most pathognomonic indicator of chronic bronchitis.
Hyperplasia and hypertrophy of mucous glands as in chronic bronchitis[2] causes them to be present at deeper levels in the bronchial wall and thicker in size, thus increasing the Reid Index beyond the normal value.
References
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Template:Eponymous medical signs for respiratory system
- ↑ B. Karger, T. Fracasso, B. Brinkmann and T. Bajanowski. Evaluation of the Reid index in infants and cases of SIDS. International Journal of Legal Medicine. Volume 118, Number 4 / August, 2004. [1]
- ↑ School of Medicine, Tulane University