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| {{enzyme
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| | Name = androst-4-ene-3,17-dione monooxygenase
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| | EC_number = 1.14.99.12
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| | CAS_number = 37256-74-9
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| | IUBMB_EC_number = 1/14/99/12
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| | GO_code = 0047096
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| In [[enzymology]], an '''androst-4-ene-3,17-dione monooxygenase''' ({{EC number|1.14.99.12}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :androst-4-ene-3,17-dione + AH<sub>2</sub> + O<sub>2</sub> <math>\rightleftharpoons</math> 3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H<sub>2</sub>O
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| The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[androst-4-ene-3,17-dione]], an [[electron acceptor]] AH<sub>2</sub>, and [[oxygen|O<sub>2</sub>]], whereas its 3 [[product (chemistry)|products]] are [[3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone]], the reduction product A, and [[water|H<sub>2</sub>O]].
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| This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is '''androst-4-ene-3,17-dione-hydrogen-donor:oxygen oxidorcockeductase (13-hydroxylating, lactonizing)'''. Other names in common use include '''androstene-3,17-dione hydroxylase''', '''androst-4-ene-3,17-dione 17-oxidoreductase''', '''androst-4-ene-3,17-dione hydroxylase''', '''androstenedione monooxygenase''', and '''4-androstene-3,17-dione monooxygenase'''. This enzyme participates in [[androgen and estrogen metabolism]].
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Prairie RL and Talalay P | date = 1963 | title = Enzymatic formation of testololactone | journal = Biochemistry | volume = 2 | pages = 203–208 | doi = 10.1021/bi00901a039 | pmid=13985909 }}
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| {{1.14-enzyme-stub}}
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| [[Category:EC 1.14.99]]
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| [[Category:Enzymes of unknown structure]]
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Hello, my title is Andrew and my spouse doesn't like it at all. Office supervising is where my main earnings comes from but I've usually wanted my own business. For years he's been residing in Alaska and he doesn't strategy on altering it. I am truly fond of handwriting but I can't make it my profession really.
Have a look at my webpage: psychics online