5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase: Difference between revisions

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{{enzyme
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| Name = (+)-abscisic acid 8'-hydroxylase
| EC_number = 1.14.13.93
| CAS_number = 153190-37-5
| IUBMB_EC_number = 1/14/13/93
| GO_code = 0010295
| image =
| width =
| caption =
}}
 
In [[enzymology]], a '''(+)-abscisic acid 8'-hydroxylase''' ({{EC number|1.14.13.93}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:(+)-abscisate + NADPH + H<sup>+</sup> + O<sub>2</sub> <math>\rightleftharpoons</math> 8'-hydroxyabscisate + NADP<sup>+</sup> + H<sub>2</sub>O
 
The four [[substrate (biochemistry)|substrates]] of this enzyme are (+)-[[abscisic acid|abscisate]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], [[hydrogen ion|H<sup>+</sup>]], and [[oxygen|O<sub>2</sub>]], whereas its three [[product (chemistry)|products]] are 8'-hydroxy-[[abscisic acid|abscisate]], [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], and [[water|H<sub>2</sub>O]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, to be specific those acting on paired donors, with O<sub>2</sub> as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O<sub>2</sub> with NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor. This enzyme participates in [[carotenoid]] [[biosynthesis]].
 
== Nomenclature ==
 
The systematic name of this enzyme class is '''abscisate,NADPH:oxygen oxidoreductase (8'-hydroxylating)'''. Other names in common use include
* (+)-ABA 8'-hydroxylase and
* ABA 8'-hydroxylase.
 
==References==
{{reflist|1}}
{{refbegin}}
* {{cite journal | author = Cutler AJ, Squires TM, Loewen MK and Balsevich JJ | year = 1997 | title = Induction of (+)-abscisic acid 8' hydroxylase by (+)-abscisic acid in cultured maize cells | journal = J. Exp. Bot.  | volume = 48 | pages = 1787&ndash;1795 }}
* {{cite journal | author = Krochko JE, Abrams GD, Loewen MK, Abrams SR, Cutler AJ | year = 1998 | title = (+)-Abscisic acid 8'-hydroxylase is a cytochrome P450 monooxygenase | journal = Plant. Physiol.  | volume = 118 | pages = 849&ndash;60  | pmid = 9808729 | doi = 10.1104/pp.118.3.849 | issue = 3 | pmc = 34795 }}
{{refend}}
 
[[Category:EC 1.14.13]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]
 
 
{{1.14.13-enzyme-stub}}

Latest revision as of 12:14, 26 May 2014

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