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| {{enzyme
| | Hi there, I am Sophia. Distributing production is how he makes a living. To play lacross is some thing I truly appreciate doing. Alaska is where I've usually been residing.<br><br>my blog post: accurate psychic readings ([http://gcjcteam.org/index.php?mid=etc_video&document_srl=696611&sort_index=regdate&order_type=desc http://gcjcteam.org/index.php?mid=etc_video&document_srl=696611&sort_index=regdate&order_type=desc]) |
| | Name = caffeate O-methyltransferase
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| | EC_number = 2.1.1.68
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| | CAS_number = 50936-45-3
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| | IUBMB_EC_number = 2/1/1/68
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| | GO_code = 0047763
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| In [[enzymology]], a '''caffeate O-methyltransferase''' ({{EC number|2.1.1.68}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[S-Adenosyl methionine|S-adenosyl methionine]] and [[3,4-dihydroxy-trans-cinnamate]] (caffeic acid), whereas its two [[product (chemistry)|products]] are [[S-adenosylhomocysteine]] and [[3-methoxy-4-hydroxy-trans-cinnamate]] (ferulic acid).
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| This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is '''S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase'''. Other names in common use include '''caffeate methyltransferase''', '''caffeate 3-O-methyltransferase''', and '''S-adenosyl-L-methionine:caffeic acid-O-methyltransferase'''. This enzyme participates in [[phenylpropanoid biosynthesis]].
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| == Structural studies == | |
| As of late 2007, two [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1KYW}} and {{PDB link|1KYZ}}.
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| == References ==
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| {{reflist|1}}
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| * {{cite journal | author = Hahlbrock K | date = 1974 | title = Coordinated changes in enzyme activities of phenylpropanoid metabolism during the growth of soybean cell suspension cultures | journal = Biochim. Biophys. Acta. | volume = 362 | pages = 417–24 | pmid = 4472044 | last2 = Schaller-Hekeler | first2 = B | last3 = Knobloch | first3 = KH | last4 = Wellman | first4 = E | last5 = Grisebach | first5 = H | last6 = Hahlbrock | first6 = K | issue = 3 }}
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| * {{cite journal | author = Poulton JE, Butt VS | date = 1975 | title = Purification and properties of S-adenosyl-L-methionine: caffeic acid O-methyltransferase from leaves of spinach beet (Beta vulgaris L) | journal = Biochim. Biophys. Acta. | volume = 403 | pages = 301–14 | pmid = 241400 | issue = 2 }}
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| * {{cite journal | author = Shimada M, Kuroda H and Higuchi T | date = 1973 | title = Evidence for the formation of methoxyl groups of ferulic and sinapic acid in Bambusa by the same O-methyltransferase | journal = [[Phytochemistry (journal)|Phytochemistry]] | volume = 12 | pages = 2873–2875 | doi = 10.1016/0031-9422(73)80498-4 | issue = 12 }}
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| [[Category:EC 2.1.1]]
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| [[Category:Enzymes of known structure]]
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| [[Category:O-Methylated hydroxycinnamic acids metabolism]]
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| {{transferase-stub}}
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Hi there, I am Sophia. Distributing production is how he makes a living. To play lacross is some thing I truly appreciate doing. Alaska is where I've usually been residing.
my blog post: accurate psychic readings (http://gcjcteam.org/index.php?mid=etc_video&document_srl=696611&sort_index=regdate&order_type=desc)