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'''Dielectrophoresis''' (or DEP) is a phenomenon in which a [[force]] is exerted on a [[dielectric]] particle when it is subjected to a non-uniform [[electric field]].<ref name=Pohl>Pohl, H. A., 1978. ''Dielectrophoresis the behavior of neutral matter in nonuniform electric fields''. Cambridge University Press. Cambridge.</ref><ref name=Morgan>Morgan, H. and Green, N. ''AC Electrokinetics: Colloids and Nanoparticles''(Research Studies Press, 2002)</ref><ref name="Hughes">Hughes, M.P. ''Nanoelectromechanics in Engineering and Biology'' (CRC Press, 2002)</ref><ref name="Jones">T. B. Jones, ''Electromechanics of particles'' (Cambridge University Press, Cambridge, 1995).</ref><ref name=Kirby>{{cite book | author=Kirby, B.J. | title=Micro- and Nanoscale Fluid Mechanics: Transport in Microfluidic Devices.| url=http://www.kirbyresearch.com/textbook| year=2010| publisher=Cambridge University Press| isbn=978-0-521-11903-0}}
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</ref><ref name=Chang>{{cite book | author=Chang, H.C. and Yao, L. | title=Electrokinetically Driven Microfluidics and Nanofluidics | year= 2009}}</ref> This force does not require the particle to be [[electric charge|charged]]. All particles exhibit dielectrophoretic activity in the presence of electric fields. However, the strength of the force depends strongly on the medium and particles' electrical properties, on the particles' shape and size, as well as on the frequency of the electric field. Consequently, fields of a particular frequency can manipulate particles with great selectivity. This has allowed, for example, the separation of cells or the orientation and manipulation of nanoparticles<ref name=Morgan/><ref name=Hughes2>Hughes, M.P. ' AC Electrokinetics: Applications for Nanotechnology’ ''Nanotechnology'' '''11''' 124-132</ref> and [http://nanotechweb.org/articles/journal/5/10/2/1 nanowires].  Furthermore, a study of the change in DEP force as a function of frequency can allow the electrical (or [[electrophysiology|electrophysiological]] in the case of cells) properties of the particle to be elucidated.


==Background and Properties==
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Although the phenomenon we now call dielectrophoresis was described in passing as far back as the early 20th century, it was only subject to serious study, named and first understood by Herbert Pohl in the 1950s.<ref>H. A. Pohl, "The Motion and Precipitation of Suspensoids in Divergent Electric Fields", ''J. Appl. Phys.'' 22(7), 869–871 (1951).</ref><ref>Pohl, H. A., 1958, "Some effects of nonuniform fields on dielectrics", ''J. Appl. Phys.'', 29(8), 1182 - 1188.</ref> Recently, dielectrophoresis has been revived due to its potential in the manipulation of [[microparticles]],<ref name=Morgan/><ref name=Jones/><ref name=Kirby/><ref>{{cite journal|last=Tathireddy|first=P.|coauthors= Choi, Y-H, Skliar, M|title=Particle AC electrokinetics in planar interdigitated microelectrode geometry|journal=Journal of Electrostatics|year=2008|volume=66|issue=11-12|pages=609–619|doi=10.1016/j.elstat.2008.09.002}}</ref>[[nanoparticles]] and [[cell (biology)|cell]]s.
 
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Dielectrophoresis occurs when a polarizable particle is suspended in a non-uniform electric field.  The electric field polarizes the particle, and the poles then experience a [[Coulomb's law|force]] along the field lines, which can be either attractive or repulsive according to the orientation on the dipole.  Since the field is non-uniform, the pole experiencing the greatest electric field will dominate over the other, and the particle will move.  The orientation of the dipole is dependent on the relative polarizability of the particle and medium, in accordance with [[Maxwell–Wagner–Sillars polarization]].  Since the direction of the force is dependent on field gradient rather than field direction, DEP will occur in AC as well as DC electric fields; polarization (and hence the direction of the force) will depend on the relative polarizabilities of particle and medium.  If the particle moves in the direction of increasing electric field, the behavior is referred to as positive DEP (sometime pDEP), if acting to move the particle away from high field regions, it is known as negative DEP (or nDEP). As the relative polarizabilities of the particle and medium are frequency-dependent, varying the energizing signal and measuring the way in which the force changes can be used to determine the electrical properties of particles; this also allows the elimination of [[electrophoresis|electrophoretic]] motion of particles due to inherent particle charge.
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Phenomena associated with dielectrophoresis are [[electrorotation]] and [[traveling wave]] dielectrophoresis (TWDEP). These require complex signal generation equipment in order to create the required rotating or traveling electric fields, and as a result of this complexity have found less favor among researchers than conventional dielectrophoresis.
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==Dielectrophoretic force==
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The simplest theoretical model is that of a homogeneous sphere surrounded by a conducting dielectric medium.<ref>Irimajiri, A., T. Hanai, and A. Inouye, Dielectric theory of multi-stratified shell-model with its application to a lymphoma cell. Journal of Theoretical Biology, 1979. 78(2): p. 251-269</ref> For a homogeneous sphere of radius <math>r</math> and complex permittivity <math>\varepsilon_p^*</math> in a medium with complex permittivity <math>\varepsilon_m^*</math> the (time-averaged) DEP force is:<ref name="Jones"/>
:<math>\langle F_\mathrm{DEP} \rangle = 2\pi r^3\varepsilon_m \textrm{Re}\left\{\frac{\varepsilon^*_p - \varepsilon^*_m}{\varepsilon^*_p + 2\varepsilon^*_m}\right\}\nabla \left|\vec{E}_{rms}\right|^2</math>


The factor in curly brackets is known as the complex [[Clausius-Mossotti relation|Clausius-Mossotti function]]<ref name=Morgan/><ref name=Jones/><ref name=Kirby/> and contains all the frequency dependence of the DEP force. Where the particle consists of nested spheres - the most common example of which is the approximation of a spherical cell composed of an inner part (the cytoplasm) surrounded by an outer layer (the cell membrane) - then this can be represented by nested expressions for the shells and the way in which they interact, allowing the properties to  be elucidated where there are sufficient parameters related to the number of unknowns being sought.
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For a more general field-aligned [[ellipsoid]] of radius <math>r</math> and length <math>l</math> with complex dielectric constant <math>\varepsilon_p^*</math> in a medium with complex dielectric constant <math>\varepsilon_m^*</math> the time-dependent dielectrophoretic force is given by:<ref name=Jones/>
 
:<math>F_\mathrm{DEP} = \frac{\pi r^2 l}{3}\varepsilon_m \textrm{Re}\left\{\frac{\varepsilon^*_p - \varepsilon^*_m}{\varepsilon^*_m}\right\}\nabla \left|\vec{E}\right|^2 </math>
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The complex dielectric constant is <math>\varepsilon^* = \varepsilon + \frac{i\sigma}{\omega}</math>, where <math>\varepsilon</math> is the [[dielectric constant]], <math>\sigma</math> is the [[electrical conductivity]], <math>\omega</math> is the field frequency, and <math>i</math> is the [[imaginary unit]].<ref name=Morgan/><ref name=Jones/><ref name=Kirby/>  This expression has been useful for approximating the dielectrophoretic behavior of particles such as [[Erythrocye|red blood cells]] (as oblate spheroids) or long thin tubes (as prolate ellipsoids) allowing the approximation of the dielectrophoretic response of [[carbon nanotubes]] or [[/Tobacco mosaic virus|tobacco mosaic viruses]] in suspension.
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These equations are accurate for particles when the electric field gradients are not very large (e.g., close to electrode edges) or when the particle is not moving along an axis in which the field gradient is zero (such as at the center of an axisymmetric electrode array), as the equations only take into account the [[dipole]] formed and not higher order [[Multipole expansion|polarization]].<ref name=Jones/> When the electric field gradients are large, or when there is a field null running through the center of the particle, higher order terms become relevant,<ref name=Jones/> and result in higher forces.
To be precise, the time-dependent equation only applies to lossless particles, because loss creates a lag between the field and the induced dipole. When averaged, the effect cancels out and the equation holds true for lossy particles as well. An equivalent time-averaged equation can be easily obtained by replacing '''''E''''' with '''''E<sub>rms</sub>''''', or, for sinusoidal voltages by dividing the right hand side by 2.
These models ignores the fact that cells have a complex internal structure and are heterogeneous. A multi-shell model in a low conducting medium can be used to obtain information of the membrane conductivity and the permittivity of the cytoplasm.<ref>Pauly, H. and H.P. Schwan, Impedance of a suspension of ball-shaped particles with a shell: a model for the dielectric behaviour of cell suspensions and protein solutions (Uber die impedanz einer suspension von kugelformigen teilchen mit einer schale -ein modell fur das dielektrische verhalten von zellsuspensionen und von proteinlosungen). Zeitschrift Fur Naturforschung Part B-Chemie Biochemie Biophysik Biologie Und Verwandten Gebiete, 1959. 14(2): p. 125-131</ref>
For a cell with a shell surrounding a homogeneous core with its surrounding medium considered as a layer, as seen in Figure 2, the overall dielectric response is obtained from a combination of the properties of the shell and core.<ref name="Broche, L.M. 2005">Broche, L.M., F.H. Labeed, and M.P. Hughes, Extraction of dielectric properties of multiple populations from dielectrophoretic collection spectrum data. Physics in Medicine and Biology, 2005. 50(10): p. 2267-2274</ref>


<math> \varepsilon_{1eff}^*(\omega)= \varepsilon_2^*\frac{(\frac{r_2}{r_1})^3+2\frac{\varepsilon_1^*-\varepsilon_2^*}{\varepsilon_1^*+2\varepsilon_2^*}}{(\frac{r_2}{r_1})^3-\frac{\varepsilon_1^*-\varepsilon_2^*}{\varepsilon_1^*+2\varepsilon_2^*}}</math>
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where 1 is the core (in cellular terms, the cytoplasm), 2 is the shell (in a cell, the membrane). r1 is the radius from the centre of the sphere to the inside of the shell, and r2 is the radius from the centre of the sphere to the outside of the shell.
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==Applications of Dielectrophoresis==
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Dielectrophoresis can be used to manipulate, transport, separate and sort different types of particles. Since biological cells have dielectric properties,<ref name="Pethig R 1979">Pethig R. Dielectric Properties of Biological Materials, 1979.</ref><ref name="Choi, J.W., Pu, A. and Psaltis, D. 2006 9780–9785">{{cite journal | author=Choi, J.W., Pu, A. and Psaltis, D. | title=Optical detection of asymmetric bacteria utilizing electro orientation | journal=Optics Express| volume=14|pages=9780–9785|year= 2006 | url=http://www.opticsinfobase.org/oe/abstract.cfm?URI=OPEX-14-21-9780|bibcode = 2006OExpr..14.9780C |doi = 10.1364/OE.14.009780 }}</ref> dielectrophoresis has many medical applications. Prototypes that separate cancer cells from healthy cells have been made.<ref name="Usage article">[http://www.electronicsweekly.com/Articles/2009/10/07/47131/micro-fluidics-cut-cancer-test-from-a-day-to-an-hour-imec-tech-forum.htm Micro-fluidics cut cancer test from a day to an hour - IMEC Tech Forum]</ref> Platelets have been separated from whole blood with a DEP-activated [[Flow cytometry|cell sorter]].<ref>[http://onlinelibrary.wiley.com/doi/10.1002/elps.200700607/abstract Pommer, MS et al., 2008. "Dielectrophoretic separation of platelets from diluted whole blood in microfluidic channels", ''Electrophoresis'', 29(6), 1213-1218.]</ref>
 
Dielectrophoresis can be used to manipulate, transport, separate and sort different types of particles. DEP is being applied in fields such as:
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*Medical diagnostics
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*Drug discovery
*Cell therapeutics
*Particle filtration


The most effort in studying DEP has been directed towards satisfying  the unmet needs in the biomedical sciences.
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As biological cells have dielectric properties <ref name="Pethig R 1979"/><ref name="Choi, J.W., Pu, A. and Psaltis, D. 2006 9780–9785"/> dielectrophoresis has many medical applications. Prototypes that separate cancer cells from healthy cells have been made.<ref name="Usage article"/>
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DEP has made it possible to characterize and manipulate biological particles like [[blood cells]], [[stem cells]], [[neurons]], pancreatic [[β cells]], [[DNA]], [[chromosomes]], [[proteins]] and [[viruses]].
DEP can be used to separate particles with different sign polarizabilities as they move in different directions at a given frequency of the AC field applied. DEP has been applied for the separation of:
*Live and dead cells, with the remaining live cells still viable after separation<ref>Pohl, H.A. and I. Hawk, Separation of living and dead cells by dielectrophoresis. Science, 1966. 152(3722): p. 647-&</ref>
*Cancer cells from blood<ref>Gascoyne, P.R.C., et al., Dielectrophoretic separation of cancer cells from blood. Ieee Transactions on Industry Applications, 1997. 33(3): p. 670-678</ref>
*Strains of [[bacteria]] and viruses<ref>Markx, G.H., P.A. Dyda, and R. Pethig, Dielectrophoretic separation of bacteria using a conductivity gradient. Journal of Biotechnology, 1996. 51(2): p. 175-180</ref><ref>Burt, J.P.H., R. Pethig, and M.S. Talary, Microelectrode devices for manipulating and analysing bioparticles. Transactions of the Institute of Measurement and Control, 1998. 20(2): p. 82-90</ref>
*Red and white blood cells
DEP can also be used to detect apoptosis soon after drug induction measuring the changes in electrophysiological properties.<ref>Chin, S., et al., Rapid assessment of early biophysical changes in K562 cells during apoptosis determined using dielectrophoresis. International Journal of Nanomedicine, 2006. 1(3): p. 333-337</ref>


===DEP as a cell characterisation tool===
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DEP is mainly used for characterising cells measuring the changes in their electrical properties. To do this, many techniques are available to quantify the dielectrophoretic response, as it is no possible to directly measure the DEP force.  
 
These techniques rely on indirect measures, obtaining a proportional response of the strength and direction of the force that needs to be scaled to the model spectrum. So most models only consider the Clausius-Mossotti factor of a particle.
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The most used techniques are:
 
*Collection rate measurements: this is the simplest and most used technique. Electrodes are submerged in a suspension with a known concentration of particles and the particles that collect at the electrode are counted.<ref>Labeed, F.H., Coley, H.M., Hughes, M.P. (2006), Biochim Biophys Acta 1760, 922-929</ref>
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*Crossover measurements: the crossover frequency between positive and negative DEP is measured to characterise particles. This technique is used for smaller particles (e.g. viruses), that are difficult to count with the previous technique.<ref>Hughes, M.P., Morgan, H., Rixon, F.J., Burt, J.P.H., Pethig, R. (1998) , Biochim Biophys Acta 1425, 119-126</ref>
 
*Particle velocity measurements: this technique measures the velocity and direction of the particles in an electric field gradient.<ref>Watarai, H., Sakomoto, T., Tsukahara, S. (1997) Langmuir 13, 2417-2420</ref>
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*Measurement of the levitation height: the levitation height of a particle is proportional to the negative DEP force that is applied. Thus, this technique is good for characterising single particles and is mainly used for larger particles such as cells.<ref>Kaler, K.V., Jones, T.B. (1990) Biophysical Journal 57, 173-182</ref>  
 
*[[Impedance]] sensing: particles collecting at the electrode edge have an influence on the impedance of the electrodes. This change can be monitored to quantify DEP.<ref>Allsop, D.W.E., Milner, K.R., Brown, A.P., Betts, W.B. (1999) Journal of Physics D: Applied Physics 32, 1066-1074</ref>
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In order to study larger populations of cells, the properties can be obtained by analysing the dielectrophoretic spectra.<ref name="Broche, L.M. 2005"/>
 
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==Implementing Dielectrophoresis==
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===Electrode geometries===
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At the start, electrodes were made mainly from wires or metal sheets.  
 
Nowadays, the electric field in DEP is created by means of electrodes which minimize the magnitude of the voltage needed. This has been possible using fabrication techniques such as photolithography, laser ablation and electron beam patterning.<ref>Suehiro, J. and R. Pethig, The dielectrophoretic movement and positioning of a biological cell using a three-dimensional grid electrode system. Journal of Physics D-Applied Physics, 1998. 31(22): p. 3298-3305</ref>
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These small electrodes allow the handling of small bioparticles.  
 
The most used electrode geometries are:
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*Isometric: this geometry is effective for particle manipulation with DEP but repelled particles do not collect in well defined areas and so separation into two homogeneous groups is difficult.
 
*Polynomial: this new geometry produced well defined differences in regions of high and low forces and so particles could be collected by positive and negative DEP. This electrode geometry showed that the electrical field was highest at the middle of the inter-electrode gaps.<ref>Huang, Y. and R. Pethig, Electrode design for negative dielectrophoresis. Measurement Science & Technology, 1991. 2(12): p. 1142-1146</ref>
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*Interdigitated: this geometry is made alternating electrode fingers of opposing polarities and is mainly used for dielectrophoretic trapping and analysis.
 
*Crossbar: this geometry is potentially useful for networks of interconnects.<ref>[[Alex Wissner-Gross|A. D. Wissner-Gross]], "[http://www.alexwg.org/link?url=http%3A%2F%2Fwww.alexwg.org%2Fpublications%2FBINICChapter_2009.pdf Dielectrophoretic architectures]", ''Bio-Inspired and Nanoscale Integrated Computing'' 155-173 (ed. M. Eshaghian-Wilner, Wiley, 2009).</ref>
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===DEP well electrodes===
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These electrodes were developed by Hoettges et al.<ref>Hoettges, K.F., et al., Dielectrophoresis-activated multiwell plate for label-free high-throughput drug assessment. Analytical Chemistry, 2008. 80(6): p. 2063-2068</ref> and offer a rapid and low cost way to quantify DEP.


A glass slide is attached to the bottom of the well to contain the sample. Successive conductive layers of the laminate are connected to the two phases of an AC signal so that the walls of the wells have electrodes of alternate [[electric potential|potential]], while the field gradient formed along the walls moves cells by DEP.<ref>Fatoyinbo, H.O., et al., A high-throughput 3-D composite dielectrophoretic separator. IEEE Transactions on Biomedical Engineering, 2005. 52(7): p. 1347-1349</ref> The dielectrophoretic properties of cells can be monitored by [[light absorption]] measurements: positive DEP attracts the cells to the wall of the well, thus when probed with a light beam the well the light intensity increases through the well.  The opposite is true for negative DEP, in which the light beam becomes obscured by the cells. This approach offers many advantages over conventional, photolithography-based devices but reducing cost, increasing the amount of sample which can be analysed simultaneously, and the simplicity of cell motion reduced ot one dimension (where cells can only move radially towards or away from the centre of the well).
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===Dielectrophoresis Field-Flow Fractionation (DEP-FFF)===
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The utilization of the difference between dielectrophoretic forces exerted on different particles in nonuniform electric fields is known as DEP separation. The exploitation of DEP forces has been classified into two groups: DEP migration and DEP retention. DEP migration uses DEP forces that exert opposite signs of force on different particle types to attract some of the particles and repel others.<ref>[[Alex Wissner-Gross|A. D. Wissner-Gross]], "[http://www.alexwg.org/publications/Nanotechnology_17-4986.pdf Dielectrophoretic reconfiguration of nanowire interconnects]", ''Nanotechnology'' 17, 4986-4990 (2006).</ref> DEP retention uses the balance between DEP and fluid-flow forces. Particles experiencing repulsive and weak attractive DEP forces are eluted by fluid flow, whereas particles experiencing strong attractive DEP forces are trapped at electrode edges against flow drag.<ref name="Gascoyne">Gascoyne, P.R.C., Y. Huang, R. Pethig, J. Vykoukal and F.F. Becker, 1992. "Dielectrophoretic separation of mammalian cells studied by computerized image analysis". ''Meas. Sci.Technol.'' 3, 439-445.</ref>


Dielectrophoresis Field-Flow Fractionation, introduced by Davis and Giddings,<ref>Davis, J.M. and J.C. Giddings, 1986. "Feasibility study of dielectrical field-flow fractionation". Sepa. ''Sci. and Tech.'' 21, 969-989.</ref> is a family of chromatographic-like separation methods. In DEP-FFF, DEP forces are combined with drag flow to fractionate a sample of different types of particles.<ref name="Gascoyne"/><ref>Giddings, J.C., 1993. "Field-Flow Fractionation: Analysis of macromolecular, colloidal, and particulate materials". ''Science''. 260, 1456-1465.</ref><ref>G.H. Markx, J. Rousselet and R. Pethig, 1997. "DEP-FFF: Field-flow fractionation using non-uniform electric fields." ''Journal of Liquid Chromatography & Related Technologies'' 20, 2857-2872</ref><ref>Huang, Y., X.B. Wang, F.F. Becker and P.R.C. Gascoyne, 1997. "Introducing dielectrophoresis as a new force field for field-flow fractionation". ''Biophys. J''. 73, 1118-1129</ref><ref>Wang, X.B., J. Vykoukal, F.F. Becker and P.R.C. Gascoyne, 1998. "Separation of polystyrene microbeads using dielectrophoretic/gravitational field-flow-fractionation". ''Biophysical Journal''. 74, 2689-2701.</ref><ref>Rousselet, G.H. Markx & R. Pethig, 1998 "Separation of erythrocytes and latex beads by dielectrophoretic levitation and hyperlayer field-flow fractionation." ''Colloids and Surfaces A''. 140, 209-216</ref> Particles are injected into a carrier flow that passes through the separation chamber, with an external separating force (a DEP force) being applied perpendicular to the flow. By means of different factors, such as diffusion and steric, hydrodynamic, dielectric and other effects, or a combination thereof, particles (<1 μm in diameter) with different dielectric or diffusive properties attain different positions away from the chamber wall, which, in turn, exhibit different characteristic concentration profile. Particles that move further away from the wall reach higher positions in the parabolic velocity profile of the liquid flowing through the chamber and will be eluted from the chamber at a faster rate.
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===Optical Dielectrophoresis===
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The use of photoconductive materials (for example, in lab-on-chip devices) allows for localized inducement of dielectrophoretic forces through the application of light. In addition, one can project an image to induce forces in a patterned illumination area, allowing for some complex manipulations. When manipulating living cells, optical dielectrophoresis provides a non-damaging alternative to [[optical tweezers]], as the intensity of light is about 1000 times less.<ref>Dongqing Li, ed. "Encyclopedia of Microfluidics and Nanofluidics". Springer, New York, 2008.</ref>


==References==
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==External links==
== A small treeMeet 7cardcha Celine Shop Online Uk ==
* [http://www.aesociety.org/areas/dielectrophoresis.php The American Electrophoresis Society: Dielectrophoresis]
* [http://www.iop.org/EJ/abstract/0305-4470/22/8/014 Dielectrophoresis: a spherical shell model]
* [http://www.ece.rochester.edu/~jones/langmuir_2002.pdf On the Relationship of Dielectrophoresis and Electrowetting]
* [http://robotics.eecs.berkeley.edu/~pister/245/project/DiazPayen.pdf Biological cell separation using dielectrophoresis in a microfluidic device]
* [http://www.physorg.com/news5980.html Sandia’s dielectrophoresis device may revolutionize sample preparation]
* [http://www.ibmm-microtech.co.uk/microeng/dielectrophoresis/dielectrophoresis.php Institute of Bioelectronic and Molecular Microsystems: Dielectrophoresis]


[[Category:Electrophoresis]]
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The most severe side-effect of advanced GERD is most likely a condition called Barrett esophagus, that is asymptomatic but potentially deadly due to its connection with cancer. GERD patients with chronic heartburn are the group most likely to develop Barrett esophagus. Within this medical condition, the tissue that lines the esophagus experiences a structural change called intestinal metaplasia, by which its cells are substituted for cells characteristic of the lining from the intestine. Between 5 and 15% of heartburn patients have Barrett Esophagus, and of these patients, about 1 in 200 (0.5%) go on to create a deadly cancer of the esophagus. White males over fifty would be the population most likely to develop cancer as a result of Barrett Esophagus. Although it is impossible to calculate which Barrett Esophagus patients will develop cancer, there is clearly rapport between the two. One more reason, then, to treat GERD in its early stages, before the damage progresses too far.

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If Marquez plays hard to get or demands a stiff purse, the Pacquiao camp won't beg him for a fifth fight, lawyer Jeng Gacal, Pacquiao's legal adviser, told the Inquirer in an earlier interview. Gacal insists only a Pacquiao fight can give the 39yearold Marquez financial security once he hangs up his gloves.

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SETI: Searching the Skies for Indications of LifeMartin AndersenJanuary 31, 2012 at 5:04Alan, it's exciting to listen to that you are working on a SETI project with LOFAR.Do you know the plans for the future with LOFAR and SETI ?Why is LOFAR only complementary to the Allen telescope arra.Life and Work on the South PoleHarrisonJanuary 16, 2012 at 1:33Hello i'm Harrison and I just have a couple question.

Journalist John Pilger included the saying in his speech accepting Australia's human rights award, the Sydney Peace Prize, on 5th November 2009: "Democracy has become a business plan, with a bottom line for every human activity, every dream, every decency, every hope. The primary parliamentary parties are now devoted to the same economic policies socialism for the rich, capitalism for that poor and the same foreign policy of servility to endless war. This is not democracy. Senator Bernie Sanders referenced the phrase during his eightandahalfhour speech on the senate floor on December 10, 2010 from the continuation of Bushera tax cuts, when talking on the federal bailout of major banking institutions at a Barbour Australia Stockist time when smallbusinesses were being denied loans. [20].

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