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| Name = 4-hydroxymandelate synthase
| EC_number = 1.13.11.46
| CAS_number =
| IUBMB_EC_number = 1/13/11/46
| GO_code = 0050585
| image =
| width =
| caption =
}}
In [[enzymology]], a '''4-hydroxymandelate synthase''' ({{EC number|1.13.11.46}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:4-hydroxyphenylpyruvate + O<sub>2</sub> <math>\rightleftharpoons</math> 4-hydroxymandelate + CO<sub>2</sub>
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[4-hydroxyphenylpyruvate]] and [[oxygen]], whereas its two [[product (chemistry)|products]] are [[4-hydroxymandelate]] and [[carbon dioxide]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on single donors with O<sub>2</sub> as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O<sub>2</sub>. The systematic name of this enzyme class is '''4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)'''. This enzyme is also called '''4-hydroxyphenylpyruvate dioxygenase II'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Choroba OW, Williams DH and Spencer JB | date = 2000 | title = Biosynthesis of the vancomycin group of antibiotics: involvement of an unusual dioxygenase in the pathway to (S)-4-hydroxyphenylglycine | journal = J. Am. Chem. Soc. | volume = 122 | issue = 22 | pages = 5389&ndash;5390 | doi = 10.1021/ja000076v }}
 
[[Category:EC 1.13.11]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 02:26, 26 April 2013

Template:Enzyme In enzymology, a 4-hydroxymandelate synthase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

4-hydroxyphenylpyruvate + O2 4-hydroxymandelate + CO2

Thus, the two substrates of this enzyme are 4-hydroxyphenylpyruvate and oxygen, whereas its two products are 4-hydroxymandelate and carbon dioxide.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating). This enzyme is also called 4-hydroxyphenylpyruvate dioxygenase II.

References

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