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| {{enzyme
| | My name is Yukiko and I am studying Environmental Management and Africana Studies at Angouleme / France.<br><br>Also visit my homepage - [http://rhinoplastygroup.com Rhinoplasty] |
| | Name = 4-amino-4-deoxychorismate synthase
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| | EC_number = 2.6.1.85
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| | CAS_number = 132264-37-0
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| | IUBMB_EC_number = 2/6/1/85
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| | GO_code = 0046820
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| In [[enzymology]], an '''aminodeoxychorismate synthase''' ({{EC number|2.6.1.85}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :chorismate + L-glutamine <math>\rightleftharpoons</math> 4-amino-4-deoxychorismate + L-glutamate
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[chorismate]] and [[L-glutamine]], whereas its two [[product (chemistry)|products]] are [[4-amino-4-deoxychorismate]] and [[L-glutamate]].
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| This enzyme belongs to the family of [[ligase]]s, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with glutamine as amido-N-donor. The systematic name of this enzyme class is '''chorismate:L-glutamine amido-ligase'''. Other names in common use include '''ADC synthase''', '''4-amino-4-deoxychorismate synthase''', and '''PabB'''. This enzyme participates in [[folate biosynthesis]].
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Ye QZ, Liu J, Walsh CT | date = 1990 | title = p-Aminobenzoate synthesis in Escherichia coli: purification and characterization of PabB as aminodeoxychorismate synthase and enzyme X as aminodeoxychorismate lyase | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 87 | pages = 9391–5 | pmid = 2251281 | doi = 10.1073/pnas.87.23.9391 | issue = 23 | pmc = 55171 }}
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| * {{cite journal | author = Viswanathan VK, Green JM, Nichols BP | date = 1995 | title = Kinetic characterization of 4-amino 4-deoxychorismate synthase from Escherichia coli | journal = J. Bacteriol. | volume = 177 | pages = 5918–23 | pmid = 7592344 | issue = 20 | pmc = 177419 }}
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| {{ligase-stub}}
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| [[Category:EC 2.6.1]]
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| [[Category:Enzymes of unknown structure]]
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Latest revision as of 13:50, 24 May 2014
My name is Yukiko and I am studying Environmental Management and Africana Studies at Angouleme / France.
Also visit my homepage - Rhinoplasty