4-hydroxyphenylpyruvate oxidase: Difference between revisions

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{{enzyme
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| Name = Aldehyde dehydrogenase (NADP+)
| EC_number = 1.2.1.4
| CAS_number = 9028-87-9
| IUBMB_EC_number = 1/2/1/4
| GO_code =
| image =
| width =
| caption =
}}
In [[enzymology]], an '''aldehyde dehydrogenase (NADP+)''' ({{EC number|1.2.1.4}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:an aldehyde + NADP<sup>+</sup> + H<sub>2</sub>O <math>\rightleftharpoons</math> an acid + NADPH + H<sup>+</sup>
 
The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[aldehyde]], [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], and [[water|H<sub>2</sub>O]], whereas its 3 [[product (chemistry)|products]] are [[acid]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is '''aldehyde:NADP+ oxidoreductase'''. Other names in common use include '''NADP+-acetaldehyde dehydrogenase''', '''NADP+-dependent aldehyde dehydrogenase''', and '''aldehyde dehydrogenase (NADP+)'''. This enzyme participates in [[caprolactam degradation]].
 
==References==
{{reflist|1}}
* {{cite journal | author = Adachi O, Matsushita K, Shinagawa E and Ameyama M | date = 1980 | title = Crystallization and properties of NADP-dependent aldehyde dehydrogenase from Gluconobacter melanogenus | journal = Agric. Biol. Chem.  | volume = 44 | pages = 155&ndash;164 }}
* Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 203-221.
* {{cite journal | author = Nakayama T | date = Tokyo | title = Acetic acid bacteria. II. Intracellular distribution of enzymes related to acetic acid fermentation, and some properties of a highly purified triphosphopyridine nucleotide (TPN)-dependent aldehyde dehydrogenase | journal = J. | volume = Biochem. | pages = 812&ndash;830 }}
* {{cite journal | author = SEEGMILLER JE | date = 1953 | title = Triphosphopyridine nucleotide-linked aldehyde dehydrogenase from yeast | journal = J. Biol. Chem.  | volume = 201 | pages = 629&ndash;37  | pmid = 13061400 | issue = 2 }}
 
{{1.2-enzyme-stub}}
 
[[Category:EC 1.2.1]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 21:06, 3 March 2014

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