Ethanolamine kinase: Difference between revisions

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{{enzyme
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| Name = gentamicin 2''-nucleotidyltransferase
| EC_number = 2.7.7.46
| CAS_number = 62213-33-6
| IUBMB_EC_number = 2/7/7/46
| GO_code = 0008871
| image =
| width =
| caption =
}}
In [[enzymology]], a '''gentamicin 2"-nucleotidyltransferase''' ({{EC number|2.7.7.46}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:nucleoside triphosphate + gentamicin <math>\rightleftharpoons</math> diphosphate + 2"-nucleotidylgentamicin
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[nucleoside triphosphate]] and [[gentamicin]], whereas its two [[product (chemistry)|products]] are [[diphosphate]] and [[2''-nucleotidylgentamicin]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those transferring phosphorus-containing [[nucleotide]] groups ([[nucleotidyltransferase]]s).  The systematic name of this enzyme class is '''NTP:gentamicin 2"-nucleotidyltransferase'''. Other names in common use include '''gentamicin 2"-adenylyltransferase''', '''aminoglycoside adenylyltransferase''', and '''gentamicin 2"-nucleotidyltransferase'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Angelatou F, Litsas SB, Kontomichalou P | date = Tokyo | title = Purification and properties of two gentamicin-modifying enzymes, coded by a single plasmid pPK237 originating from Pseudomonas aeruginosa | journal = J.  | volume = Antibiot. | pages = 235&ndash;44  | pmid = 6281224 | issue = 2 }}
* {{cite journal | author = Naganawa H, Yagisawa M, Kondo S, Takeuchi T, Umezawa H | date = Tokyo | title = The structure determination of an enzymatic inactivation product of 3',4'-dideoxykanamycin B | journal = J. | volume = Antibiot. | pages = 913&ndash;4  | pmid = 4946513 | issue = 12 }}
* {{cite journal | author = Yagisawa M, Naganawa H, Kondo S, Hamada M, Takeuchi T | date = Tokyo | title = Adenylyldideoxykanamycin B, a product of the inactivation of dideoxykanamycin B by Escherichia coli carrying R factor | journal = J. | volume = Antibiot. | pages = 911&ndash;2  | pmid = 4946512 | issue = 12 }}
 
{{DEFAULTSORT:Gentamicin 2-nucleotidyltransferase}}
[[Category:EC 2.7.7]]
[[Category:Enzymes of unknown structure]]
 
 
{{enzyme-stub}}

Latest revision as of 13:49, 15 May 2014

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Feel free to visit my web page; Ugg España