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{{enzyme
| Name = sterol esterase
| EC_number = 3.1.1.13
| CAS_number = 9026-00-0
| IUBMB_EC_number = 3/1/1/13
| GO_code = 0004771
| image =
| width =
| caption =
}}
In [[enzymology]], a '''sterol esterase''' ({{EC number|3.1.1.13}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:steryl ester + H<sub>2</sub>O <math>\rightleftharpoons</math> sterol + fatty acid

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[steryl ester]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[sterol]] and [[fatty acid]].

This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on carboxylic [[ester]] bonds. The systematic name of this enzyme class is '''steryl-ester acylhydrolase'''. Other names in common use include '''cholesterol esterase''', '''cholesteryl ester synthase''', '''triterpenol esterase''', '''cholesteryl esterase''', '''cholesteryl ester hydrolase''', '''sterol ester hydrolase''', '''cholesterol ester hydrolase''', '''cholesterase''', and '''acylcholesterol lipase'''. This enzyme participates in [[bile acid biosynthesis]].

==Structural studies==

As of late 2007, two [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1AQL}} and {{PDB link|2BCE}}.

==References==
{{reflist|1}}
* {{cite journal | author = Hyun J, Kothari H, Herm E, Mortenson J, Treadwell CR, Vahouny GV | date = 1969 | title = Purification and properties of pancreatic juice cholesterol esterase | journal = J. Biol. Chem. | volume = 244 | pages = 1937–45 | pmid = 5780846 | issue = 7 }}
* {{cite journal | author = Okawa Y, Yamaguchi T | date = Tokyo | title = Studies on sterol-ester hydrolase from Fusarium oxysporum. I Partial purification and properties | journal = J. | volume = Biochem. | pages = 1209–15 | pmid = 19426 | issue = 5 }}
* {{cite journal | author = Vahouny GV, Treadwell CR | date = 1968 | title = Enzymatic synthesis and hydrolysis of cholesterol esters | journal = Methods. Biochem. Anal. | volume = 16 | pages = 219–72 | pmid = 4877146 | doi = 10.1002/9780470110348.ch4 | series = Methods of Biochemical Analysis | isbn = 978-0-470-11034-8 }}
* {{cite journal | author = Warnaar F | date = 1987 | title = Triterpene ester synthesis in latex of Euphorbia species | journal = [[Phytochemistry (journal)|Phytochemistry]] | volume = 26 | pages = 2715–2721 | doi = 10.1016/S0031-9422(00)83578-5 | issue = 10 }}

[[Category:EC 3.1.1]]
[[Category:Enzymes of known structure]]

{{hydrolase-stub}}

Retinyl-palmitate esterase - Revision history

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