https://en.formulasearchengine.com/index.php?action=history&feed=atom&title=Multiple_of_the_medianMultiple of the median - Revision history2026-04-27T07:26:58ZRevision history for this page on the wikiMediaWiki 1.43.0-wmf.28https://en.formulasearchengine.com/index.php?title=Multiple_of_the_median&diff=18433&oldid=preven>Rfde222 at 22:33, 2 December 20132013-12-02T22:33:40Z<p></p>
<p><b>New page</b></p><div>{{enzyme<br />
| Name = 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase<br />
| EC_number = 2.1.1.99<br />
| CAS_number = 113478-40-3<br />
| IUBMB_EC_number = 2/1/1/99<br />
| GO_code = 0030768<br />
| image = <br />
| width = <br />
| caption = <br />
}}<br />
In [[enzymology]], a '''3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase''' ({{EC number|2.1.1.99}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]<br />
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:S-adenosyl-L-methionine + 3-hydroxy-16-methoxy-2,3-dihydrotabersonine <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + deacetoxyvindoline<br />
<br />
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[S-Adenosyl methionine|S-adenosyl methionine]] and [[3-hydroxy-16-methoxy-2,3-dihydrotabersonine]], whereas its two [[product (chemistry)|products]] are [[S-adenosylhomocysteine]] and [[deacetoxyvindoline]].<br />
<br />
This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is '''S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase'''. Other names in common use include '''16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase''', '''NMT''', '''16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase''', '''S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine''', and '''N-methyltransferase'''. This enzyme participates in [[indole and ipecac alkaloid biosynthesis]]. <br />
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==References==<br />
{{reflist|1}}<br />
* {{cite journal | author = Foucher AL, McIntosh A, Douce G, Wastling J, Tait A, Turner CM | date = 2006 | title = A proteomic analysis of arsenical drug resistance in Trypanosoma brucei | journal = Proteomics. | volume = 6 | pages = 2726&ndash;32 | pmid = 16526094 | doi = 10.1002/pmic.200500419 | issue = 9 }}<br />
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{{transferase-stub}}<br />
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[[Category:EC 2.1.1]]<br />
[[Category:Enzymes of unknown structure]]</div>en>Rfde222