en>Wheeke: removed Category:Aviation; added Category:Aviation meteorology using HotCat

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removed Category:Aviation; added Category:Aviation meteorology using HotCat

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{{Infobox enzyme
| Name = 4-hydroxybutanoyl-CoA dehydratase
| EC_number = 4.2.1.120
| CAS_number =
| IUBMB_EC_number = 4/2/1/120
| GO_code =
| image =
| width =
| caption =
}}
'''4-hydroxybutanoyl-CoA dehydratase''' ({{EC number|4.2.1.120}}) is an [[enzyme]] with system name ''4-hydroxybutanoyl-CoA hydro-lyase''.<ref>{{cite journal | title = A vinylacetyl isomerase from ''Clostridium kluyveri'' |author = Bartsch, R.G. and Barker, H.A. |journal = Arch. Biochem. Biophys. |year = 1961 |volume = 92 |pages = 122–132 |pmid = 13687513}}</ref><ref>{{cite journal | title = Succinate-ethanol fermentation in ''Clostridium kluyveri'': purification and characterisation of 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA Δ3-Δ2-isomerase |author = Scherf, U., Sohling, B., Gottschalk, G., Linder, D. and Buckel, W. |journal = Arch. Microbiol. |year = 1994 |volume = 161 |pages = 239–245 |pmid = 8161284 |issue=3}}</ref><ref>{{cite journal | title = Purification and properties of an iron-sulfur and FAD-containing 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA Δ3-Δ2-isomerase from ''Clostridium aminobutyricum'' |author = Scherf, U. and Buckel, W. |journal = Eur. J. Biochem. |year = 1993 |volume = 215 |pages = 421–429 |pmid = 8344309 |issue=2}}</ref><ref>{{cite journal | title = 4-Hydroxybutyryl-CoA dehydratase from ''Clostridium aminobutyricum'': characterization of FAD and iron-sulfur clusters involved in an overall non-redox reaction |author = Muh, U., Cinkaya, I., Albracht, S.P. and Buckel, W. |journal = Biochemistry |year = 1996 |volume = 35 |pages = 11710–11718 |pmid = 8794752 |doi=10.1021/bi9601363 |issue=36}}</ref><ref>{{cite journal | title = A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in ''Archaea'' |author = Berg, I.A., Kockelkorn, D., Buckel, W. and Fuchs, G. |journal = Science |year = 2007 |volume = 318 |pages = 1782–1786 |pmid = 18079405 |doi=10.1126/science.1149976}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: 4-hydroxybutanoyl-CoA <math>\rightleftharpoons</math> but-3-enoyl-CoA + H2O

This enzyme contains FAD and a [4Fe-4S] iron-sulfur cluster.

== References ==
{{reflist}}

== External links ==
* {{MeshName|4-hydroxybutanoyl-CoA+dehydratase}}

[[Category:EC 4.2.1]]

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en>Wheeke: removed Category:Aviation; added Category:Aviation meteorology using HotCat