https://en.formulasearchengine.com/index.php?action=history&feed=atom&title=Alpha%2Calpha-trehalose_synthase Alpha,alpha-trehalose synthase - Revision history 2026-04-22T08:58:39Z Revision history for this page on the wiki MediaWiki 1.43.0-wmf.28 https://en.formulasearchengine.com/index.php?title=Alpha,alpha-trehalose_synthase&diff=29052&oldid=prev en>Mrt3366: minor edts using AWB (8853) 2013-03-12T12:20:32Z <p>minor edts using <a href="/index.php?title=Testwiki:AWB&amp;action=edit&amp;redlink=1" class="new" title="Testwiki:AWB (page does not exist)">AWB</a> (8853)</p> <p><b>New page</b></p><div>{{Infobox enzyme<br /> | Name = Dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase<br /> | EC_number = 2.4.1.258<br /> | CAS_number = <br /> | IUBMB_EC_number = 2/4/1/258<br /> | GO_code = <br /> | image = <br /> | width = <br /> | caption =<br /> }}<br /> &#039;&#039;&#039;Dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase&#039;&#039;&#039; ({{EC number|2.4.1.258}}, &#039;&#039;Man5GlcNAc2-PP-Dol mannosyltransferase&#039;&#039;, &#039;&#039;[[ALG3]]&#039;&#039;, &#039;&#039;dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase&#039;&#039;, &#039;&#039;Not56-like protein&#039;&#039;, &#039;&#039;Alg3 alpha-1,3-mannosyl transferase&#039;&#039;, &#039;&#039;Dol-P-Man:Man5GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase&#039;&#039;) is an [[enzyme]] with system name &#039;&#039;dolichyl beta-D-mannosyl phosphate:D-Man-alpha-(1-&gt;2)-D-Man-alpha-(1-&gt;2)-D-Man-alpha-(1-&gt;3)-(D-Man-alpha-(1-&gt;6))-D-Man-beta-(1-&gt;4)-D-GlcNAc-beta-(1-&gt;4)-D-GlcNAc-diphosphodolichol alpha-1,3-mannosyltransferase&#039;&#039;.&lt;ref&gt;{{cite journal | title = Biosynthesis of lipid-linked oligosaccharides in yeast: the ALG3 gene encodes the Dol-&#039;&#039;P&#039;&#039;-Man:Man&lt;sub&gt;5&lt;/sub&gt;GlcNAc&lt;sub&gt;2&lt;/sub&gt;-&#039;&#039;PP&#039;&#039;-Dol mannosyltransferase |author = Sharma, C.B., Knauer, R. and Lehle, L. |journal = Biol. Chem. |year = 2001 |volume = 382 |pages = 321–328 |pmid = 11308030}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = The accumulation of Man(6)GlcNAc(2)-&#039;&#039;PP&#039;&#039;-dolichol in the &#039;&#039;Saccharomyces cerevisiae&#039;&#039; &amp;Delta;&#039;&#039;alg9&#039;&#039; mutant reveals a regulatory role for the Alg3p &amp;alpha;1,3-Man middle-arm addition in downstream oligosaccharide-lipid and glycoprotein glycan processing |author = Cipollo, J.F. and Trimble, R.B. |journal = J. Biol. Chem. |year = 2000 |volume = 275 |pages = 4267–4277 |pmid = 10660594}}&lt;/ref&gt; This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]<br /> <br /> : dolichyl beta-D-mannosyl phosphate + D-Man-alpha-(1-&gt;2)-D-Man-alpha-(1-&gt;2)-D-Man-alpha-(1-&gt;3)-[D-Man-alpha-(1-&gt;6)]-D-Man-beta-(1-&gt;4)-D-GlcNAc-beta-(1-&gt;4)-D-GlcNAc-diphosphodolichol &lt;math&gt;\rightleftharpoons&lt;/math&gt; D-Man-alpha-(1-&gt;2)-D-Man-alpha-(1-&gt;2)-D-Man-alpha-(1-&gt;3)-[D-Man-alpha-(1-&gt;3)-D-Man-alpha-(1-&gt;6)]-D-Man-beta-(1-&gt;4)-D-GlcNAc-beta-(1-&gt;4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate<br /> <br /> The formation of N-glycosidic linkages of [[glycoprotein]]s involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl diphosphate.<br /> <br /> == References ==<br /> {{reflist}}<br /> <br /> == External links ==<br /> * {{MeshName|Dolichyl-P-Man:Man5GlcNAc2-PP-dolichol+alpha-1,3-mannosyltransferase}}<br /> <br /> [[Category:EC 2.4.1]]</div> en>Mrt3366