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{{enzyme
| Name = adenosylmethionine hydrolase
| EC_number = 3.3.1.2
| CAS_number = 37288-62-3
| IUBMB_EC_number = 3/3/1/2
| GO_code = 0047626
| image = 
| width = 
| caption = 
}}
In [[enzymology]], an '''adenosylmethionine hydrolase''' ({{EC number|3.3.1.2}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:S-adenosyl-L-methionine + H<sub>2</sub>O <math>\rightleftharpoons</math> L-homoserine + methylthioadenosine

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[S-adenosyl-L-methionine]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[L-homoserine]] and [[methylthioadenosine]].

This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on ether bonds involving sulfur (thioether and trialkylsulfonium hydrolases).  The systematic name of this enzyme class is '''S-adenosyl-L-methionine hydrolase'''. Other names in common use include '''S-adenosylmethionine cleaving enzyme''', '''methylmethionine-sulfonium-salt hydrolase''', and '''adenosylmethionine lyase'''.  

==References==
{{reflist|1}}
* {{cite journal | author = Mazelis M, Levin B, Mallinson N | date = 1965 | title = Decomposition of methyl methionine sulfonium salts by a bacterial enzyme | journal = Biochim. Biophys. Acta.  | volume = 105 | pages = 106&ndash;14  | pmid = 5849106 | issue = 1 }}

{{hydrolase-stub}}

[[Category:EC 3.3.1]]
[[Category:Enzymes of unknown structure]]