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{{enzyme
| Name = thiamin diphosphate kinase
| EC_number = 2.7.4.15
| CAS_number = 9075-79-0
| IUBMB_EC_number = 2/7/4/15
| GO_code = 0050331
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''thiamine-diphosphate kinase''' is an [[enzyme]] involved in [[thiamine metabolism]]. It [[catalysis|catalyzes]] the [[chemical reaction]]

:thiamine diphosphate + ATP <math>\rightleftharpoons</math> thiamine triphosphate + ADP

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]] and [[thiamine diphosphate]], whereas its two [[product (chemistry)|products]] are [[adenosine diphosphate|ADP]] and [[thiamine triphosphate]].

This enzyme belongs to the family of [[transferase]]s, specifically those transferring phosphorus-containing groups ([[phosphotransferase]]s) with a phosphate group as acceptor.  The systematic name of this enzyme class is '''ATP:thiamine-diphosphate phosphotransferase'''. Other names in common use include '''ATP:thiamin-diphosphate phosphotransferase''', '''TDP kinase''', '''thiamin diphosphate kinase''', '''thiamin diphosphate phosphotransferase''', '''thiamin pyrophosphate kinase''', '''thiamine diphosphate kinase''', and '''protein bound thiamin diphosphate:ATP phosphoryltransferase'''.
==See also==
* [[Thiamine-triphosphatase]]

==References==
{{reflist|1}}
* {{cite journal | author = Itokawa Y, Cooper JR | date = 1968 | title = The enzymatic synthesis of triphosphothiamin | journal = Biochim. Biophys. Acta.  | volume = 158 | pages = 180&ndash;2  | pmid = 5661031 | issue = 1 }}
* {{cite journal | author = Kikuchi M and Ikawa T | date = Tokyo | title = Presence of an enzyme mediating transfer of phosphate from thiamine triphosphate to ADP in germinating maize | journal = Bot.  | volume = Mag. | pages = 193&ndash;205 }}


{{Kinases}}

{{enzyme-stub}}

[[Category:EC 2.7.4]]
[[Category:Enzymes of unknown structure]]