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{{Infobox enzyme
| Name = ACP-SH:acetate ligase
| EC_number = 6.2.1.35
| CAS_number = 
| IUBMB_EC_number = 6/2/1/35
| GO_code = 
| image = 
| width = 
| caption =
}}
'''ACP-SH:acetate ligase''' ({{EC number|6.2.1.35}}, ''HS-acyl-carrier protein:acetate ligase'', ''[acyl-carrier protein]:acetate ligase'', ''MadH'') is an [[enzyme]] with system name ''acetate:(acyl-carrier-protein) ligase (AMP-forming)''.<ref>{{cite journal | title = Malonate decarboxylase of <em>Malonomonas rubra</em>, a novel type of biotin-containing acetyl enzyme |author = Hilbi, H., Dehning, I., Schink, B. and Dimroth, P. |journal = Eur. J. Biochem. |year = 1992 |volume = 207 |pages = 117–123 |pmid = 1628643}}</ref><ref>{{cite journal | title = The acyl carrier protein of malonate decarboxylase of <em>Malonomonas rubra</em> contains 2&prime;-(5"-phosphoribosyl)-3&prime;-dephosphocoenzyme A as a prosthetic  group |author = Berg, M., Hilbi, H. and Dimroth, P. |journal = Biochemistry |year = 1996 |volume = 35 |pages = 4689–4696 |pmid = 8664258}}</ref><ref>{{cite journal | title = Sequence of a gene cluster from <em>Malonomonas rubra</em> encoding components of the malonate decarboxylase Na<small><sup>+</sup></small> pump and evidence for their function |author = Berg, M., Hilbi, H. and Dimroth, P. |journal = Eur. J. Biochem. |year = 1997 |volume = 245 |pages = 103–115 |pmid = 9128730}}</ref><ref>{{cite journal | title = Enzymic and genetic basis for bacterial growth on malonate |author = Dimroth, P. and Hilbi, H. |journal = Mol. Microbiol. |year = 1997 |volume = 25 |pages = 3–10 |pmid = 11902724}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: ATP + [[acetat]]e + an [acyl-carrier protein] <math>\rightleftharpoons</math> AMP + [[diphosphate]] + an acetyl-[acyl-carrier protein]

This enzyme, from the anaerobic bacterium ''[[Malonomonas rubra]]'', is a component of the multienzyme complex [[EC 4.1.1.89]], biotin-dependent malonate decarboxylase. 

== References ==
{{reflist}}

== External links ==
* {{MeshName|ACP-SH:acetate+ligase}}

[[Category:EC 6.2.1]]