View source for Hydroquinone 1,2-dioxygenase

{{Infobox enzyme
| Name = Nitronate monooxygenase
| EC_number = 1.13.12.16
| CAS_number = 
| IUBMB_EC_number = 1/13/12/16
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Nitronate monooxygenase''' ({{EC number|1.13.12.16}}, ''NMO'') is an [[enzyme]] with system name ''nitronate:oxygen 2-oxidoreductase (nitrite-forming)''.<ref>{{cite journal | title = Involvement of a flavosemiquinone in the enzymatic oxidation of nitroalkanes catalyzed by 2-nitropropane dioxygenase |author = Francis, K., Russell, B. and Gadda, G. |journal = J. Biol. Chem. |year = 2005 |volume = 280 |pages = 5195–5204 |pmid = 15582992 |doi=10.1074/jbc.M411249200}}</ref><ref>{{cite journal | title = Crystal structure of 2-nitropropane dioxygenase complexed with FMN and substrate. Identification of the catalytic base |author = Ha, J.Y., Min, J.Y., Lee, S.K., Kim, H.S., Kim do, J., Kim, K.H., Lee, H.H., Kim, H.K., Yoon, H.J. and Suh, S.W. |journal = J. Biol. Chem. |year = 2006 |volume = 281 |pages = 18660–18667 |pmid = 16682407 |doi=10.1074/jbc.M601658200}}</ref><ref>{{cite journal | title = Nitronate monooxygenase, a model for anionic flavin semiquinone intermediates in oxidative catalysis |author = Gadda, G. and Francis, K. |journal = Arch. Biochem. Biophys. |year = 2010 |volume = 493 |pages = 53–61 |pmid = 19577534 |doi=10.1016/j.abb.2009.06.018 |issue=1}}</ref><ref>{{cite journal | title = Kinetic evidence for an anion binding pocket in the active site of nitronate monooxygenase |author = Francis, K. and Gadda, G. |journal = Bioorg. Chem. |year = 2009 |volume = 37 |pages = 167–172 |pmid = 19683782 |doi=10.1016/j.bioorg.2009.07.005 |issue=5}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[ethylnitronate]] + O<sub>2</sub> <math>\rightleftharpoons</math> [[acetaldehyde]] + [[nitrite]] + other products

The enzymes from the [[fungus]] ''[[Neurospora crassa]]'' and the [[yeast]] ''[[Williopsis saturnus]] var. mrakii'' contain non-covalently bound FMN as the cofactor. 
== References ==
{{reflist}}

== External links ==
* {{MeshName|Nitronate+monooxygenase}}

[[Category:EC 1.13.12]]