View source for HPO formalism

{{enzyme
| Name = salicylaldehyde dehydrogenase
| EC_number = 1.2.1.65
| CAS_number = 
| IUBMB_EC_number = 1/2/1/65
| GO_code = 0018485
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''salicylaldehyde dehydrogenase''' ({{EC number|1.2.1.65}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:salicylaldehyde + NAD<sup>+</sup> + H<sub>2</sub>O <math>\rightleftharpoons</math> salicylate + NADH + 2 H<sup>+</sup>

The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[salicylaldehyde]], [[nicotinamide adenine dinucleotide|NAD<sup>+</sup>]], and [[water|H<sub>2</sub>O]], whereas its 3 [[product (chemistry)|products]] are [[salicylate]], [[nicotinamide adenine dinucleotide|NADH]], and [[hydrogen ion|H<sup>+</sup>]].

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor.  The systematic name of this enzyme class is '''salicylaldehyde:NAD+ oxidoreductase'''. This enzyme participates in [[naphthalene]] and [[anthracene]] degradation.  

==References==
{{reflist|1}}
* {{cite journal | author = Eaton RW, Chapman PJ | date = 1992 | title = Bacterial metabolism of naphthalene: construction and use of recombinant bacteria to study ring cleavage of 1,2-dihydroxynaphthalene and subsequent reactions | journal = J. Bacteriol.  | volume = 174 | pages = 7542&ndash;54  | pmid = 1447127 | issue = 23 | pmc = 207464 }}

{{1.2-enzyme-stub}}

[[Category:EC 1.2.1]]
[[Category:NADH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]