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{{enzyme
| Name = galactose 1-dehydrogenase
| EC_number = 1.1.1.48
| CAS_number = 9028-54-0
| IUBMB_EC_number = 1/1/1/48
| GO_code = 0019151
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''galactose 1-dehydrogenase''' ({{EC number|1.1.1.48}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:D-galactose + NAD<sup>+</sup> <math>\rightleftharpoons</math> D-galactono-1,4-lactone + NADH + H<sup>+</sup>

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[D-galactose]] and [[nicotinamide adenine dinucleotide|NAD<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[D-galactono-1,4-lactone]], [[nicotinamide adenine dinucleotide|NADH]], and [[hydrogen ion|H<sup>+</sup>]].

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is '''D-galactose:NAD<sup>+</sup> 1-oxidoreductase'''. Other names in common use include '''D-galactose dehydrogenase''', '''beta-galactose dehydrogenase''', and '''NAD<sup>+</sup>-dependent D-galactose dehydrogenase'''. This enzyme participates in [[galactose metabolism]].

==References==
{{reflist|1}}
* {{cite journal | author = De Ley J, Doudoroff M | year = 1957 | title = The metabolism of D-galactose in ''Pseudomonas saccharophila'' | journal = J. Biol. Chem. | volume = 227 | pages = 745&ndash;57 | pmid = 13462997 | issue = 2 }}
* {{cite journal | author = Hu, ASL and Cline AL | year = 1964 | title = The regulation of some sugar dehydrogenases in a pseudomonad | journal = Biochim. Biophys. Acta | volume = 93 | pages = 237&ndash;245 | pmid=14251301}}

[[Category:EC 1.1.1]]
[[Category:NADH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]

{{1.1.1-enzyme-stub}}