View source for A-1,4-glucan-protein synthase (UDP-forming)

{{Infobox enzyme
| Name = Beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase
| EC_number = 2.4.1.163
| CAS_number = 85638-39-7
| IUBMB_EC_number = 2/4/1/163
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase''' ({{EC number|2.4.1.163}}, ''uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase'', ''poly-N-acetyllactosamine extension enzyme'', ''UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase'') is an [[enzyme]] with system name ''UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide 3-beta-N-acetylglucosaminyltransferase''.<ref>{{cite journal | title = Biosynthesis <em>in vitro</em> of Ii core glycosphingolipids from neolactotetraosylceramide by &beta; 1-3- and &beta; 1-6-<em>N</em>-acetylglucosaminyltransferases from mouse T-lymphoma |author = Basu, M. and Basu, S. |journal = J. Biol. Chem. |date = 1984 |volume = 259 |pages = 12557-12562 |pmid = 6238026}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[UDP-N-acetyl-D-glucosamine]] + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <math>\rightleftharpoons</math> UDP + N-acetyl-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

This enzyme requires Mn<sup>2+</sup>.

== References ==
{{reflist}}

== External links ==
* {{MeshName|Beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide+beta-1,3-acetylglucosaminyltransferase}}

[[Category:EC 2.4.1]]