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{{enzyme
| Name = dolichyldiphosphatase
| EC_number = 3.6.1.43
| CAS_number = 73361-26-9
| IUBMB_EC_number = 3/6/1/43
| GO_code = 0047874
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''dolichyldiphosphatase''' ({{EC number|3.6.1.43}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:dolichyl diphosphate + H<sub>2</sub>O <math>\rightleftharpoons</math> dolichyl phosphate + phosphate

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[dolichyl diphosphate]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[dolichyl phosphate]] and [[phosphate]].

This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on acid anhydrides in phosphorus-containing anhydrides.  The systematic name of this enzyme class is '''dolichyl-diphosphate phosphohydrolase'''. Other names in common use include '''dolichol diphosphatase''', '''dolichyl pyrophosphatase''', '''dolichyl pyrophosphate phosphatase''', '''dolichyl diphosphate phosphohydrolase''', and '''Dol-P-P phosphohydrolase'''.  This enzyme participates in [[n-glycan biosynthesis]].  

==References==
{{reflist|1}}
* {{cite journal | author = Naumov AV, Shabalin YA, Vagabov VM and Kulaev IS | date = Moscow | title = Two pathways of dephosphorylation of dolichyl diphosphate in yeasts | journal = B | volume = Biochemistry | pages = 551&ndash;556 }}

{{hydrolase-stub}}

[[Category:EC 3.6.1]]
[[Category:Enzymes of unknown structure]]